Performance of Oropharyngeal Swab Testing Compared With Nasopharyngeal Swab Testing for Diagnosis of Coronavirus Disease 2019-United States, January 2020-February 2020.


Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN: 1537-6591
Titre abrégé: Clin Infect Dis
Pays: United States
ID NLM: 9203213

Informations de publication

Date de publication:
01 02 2021
Historique:
received: 08 05 2020
accepted: 12 06 2020
entrez: 2 2 2021
pubmed: 3 2 2021
medline: 7 2 2021
Statut: ppublish

Résumé

Among 146 nasopharyngeal (NP) and oropharyngeal (OP) swab pairs collected ≤7 days after illness onset, Real-Time Reverse Transcriptase Polymerase Chain Reaction assay for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 RT-PCR) diagnostic results were 95.2% concordant. However, NP swab cycle threshold values were lower (indicating more virus) in 66.7% of concordant-positive pairs, suggesting NP swabs may more accurately detect the amount of SARS-CoV-2.

Identifiants

pubmed: 33527126
pii: 5858273
doi: 10.1093/cid/ciaa759
pmc: PMC7337670
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

482-485

Informations de copyright

Published by Oxford University Press for the Infectious Diseases Society of America 2020.

Références

J Clin Microbiol. 2009 Nov;47(11):3439-43
pubmed: 19726607
PLoS One. 2011;6(6):e21610
pubmed: 21738731
N Engl J Med. 2020 Mar 19;382(12):1177-1179
pubmed: 32074444
Nature. 2020 May;581(7809):465-469
pubmed: 32235945

Auteurs

Monita R Patel (MR)

Centers for Disease Control and Prevention, COVID-19 Response Team, Atlanta, Georgia, USA.

Darin Carroll (D)

Centers for Disease Control and Prevention, COVID-19 Response Team, Atlanta, Georgia, USA.

Emily Ussery (E)

Centers for Disease Control and Prevention, COVID-19 Response Team, Atlanta, Georgia, USA.

Hilary Whitham (H)

Centers for Disease Control and Prevention, COVID-19 Response Team, Atlanta, Georgia, USA.

Christopher A Elkins (CA)

Centers for Disease Control and Prevention, COVID-19 Response Team, Atlanta, Georgia, USA.

Judith Noble-Wang (J)

Centers for Disease Control and Prevention, COVID-19 Response Team, Atlanta, Georgia, USA.

James Kamile Rasheed (JK)

Centers for Disease Control and Prevention, COVID-19 Response Team, Atlanta, Georgia, USA.

Xiaoyan Lu (X)

Centers for Disease Control and Prevention, COVID-19 Response Team, Atlanta, Georgia, USA.

Stephen Lindstrom (S)

Centers for Disease Control and Prevention, COVID-19 Response Team, Atlanta, Georgia, USA.

Virginia Bowen (V)

Centers for Disease Control and Prevention, COVID-19 Response Team, Atlanta, Georgia, USA.

Jessica Waller (J)

Centers for Disease Control and Prevention, COVID-19 Response Team, Atlanta, Georgia, USA.

Gregory Armstrong (G)

Centers for Disease Control and Prevention, COVID-19 Response Team, Atlanta, Georgia, USA.

Susan Gerber (S)

Centers for Disease Control and Prevention, COVID-19 Response Team, Atlanta, Georgia, USA.

John T Brooks (JT)

Centers for Disease Control and Prevention, COVID-19 Response Team, Atlanta, Georgia, USA.

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Classifications MeSH