Arginase 1
MDSC
T helper cells
autoimmune skin blistering disease
autoimmunity
desmoglein
Journal
Experimental dermatology
ISSN: 1600-0625
Titre abrégé: Exp Dermatol
Pays: Denmark
ID NLM: 9301549
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
revised:
11
01
2021
received:
20
10
2020
accepted:
28
01
2021
pubmed:
3
2
2021
medline:
23
3
2022
entrez:
2
2
2021
Statut:
ppublish
Résumé
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells, which are characterized by their capability to suppress T-cell responses. While MDSCs have been traditionally associated with cancer diseases, their role as regulators of autoimmune diseases is emerging. Pemphigus is a chronic autoimmune blistering skin disease characterized by dysregulated T-cell responses and autoantibody production. The role of MDSCs in pemphigus disease has not been defined yet. The aim of this study was to characterize MDSCs in pemphigus patients and to dissect their relationship with CD4
Substances chimiques
Arginase
EC 3.5.3.1
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
782-791Informations de copyright
© 2021 The Authors. Experimental Dermatology published by John Wiley & Sons.
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