The effect of gluten-free diet on body mass index in paediatric celiac disease.
BMI
celiac
children
gluten-free diet
Journal
Acta paediatrica (Oslo, Norway : 1992)
ISSN: 1651-2227
Titre abrégé: Acta Paediatr
Pays: Norway
ID NLM: 9205968
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
revised:
26
01
2021
received:
07
11
2020
accepted:
29
01
2021
pubmed:
3
2
2021
medline:
6
8
2021
entrez:
2
2
2021
Statut:
ppublish
Résumé
More normal weight and overweight children are currently diagnosed with celiac disease (CD). We aimed to describe the relation between body mass index (BMI) and the clinical characteristics of paediatric CD and to determine the effect of a gluten-free diet (GFD) on BMI. Data on all children diagnosed with CD during 7/2010-7/2019 with documented anthropometric data at diagnosis were retrospectively analysed. The children were divided into three groups according to BMI status at diagnosis: underweight, normal weight and overweight (BMIs <5%, 5%-85% and >85%, respectively). Of the 236 children [median age 7.87 (4.91-11) years] included in the study, 24 (10.1%) were underweight at diagnosis and 32 (13.6%) were overweight. Diarrhoea as the presenting symptom was significantly more common in the overweight group (p = 0.012), while short stature was more common in the underweight group (p = 0.002). Following a GFD had no significant effect on the children's BMI during a median follow-up of 15.7 (0-85) months, but there was a significant shift of patients between the BMI categories (p < 0.001). Although a shift of patients between the BMI categories was observed, following a GFD did not significantly affect the overall BMI in children with CD.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2233-2239Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2021 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.
Références
Husby S, Koletzko S, Korponay-Szabó I, et al. European society paediatric gastroenterology, hepatology and nutrition guidelines for diagnosing coeliac disease 2020. J Pediatr Gastroenterol Nutr. 2020;70:141-157.
Rampertab SD, Pooran N, Brar P, Singh P, Green PH. Trends in the presentation of celiac disease. Am J Med. 2006;119:355.e9-355.e14.
Dickey W, Kearney N. Overweight in celiac disease: prevalence, clinical characteristics, and effect of a gluten-free diet. Am J Gastroenterol. 2006;101:2356-2359.
Guandalini S, Assiri A. Celiac disease: a review. JAMA Pediatr. 2014;168:272-278.
Telega G, Bennet TR, Werlin S. Emerging new clinical patterns in the presentation of celiac disease. Arch Pediatr Adolesc Med. 2008;162:164-168.
Roma E, Panayiotou J, Karantana H, et al. Changing pattern in the clinical presentation of pediatric celiac disease: a 30-year study. Digestion. 2009;80:185-191.
Fasano A, Catassi C. Current approaches to diagnosis and treatment of celiac disease: an evolving spectrum. Gastroenterology. 2001;120:636-651.
Kabbani TA, Goldberg A, Kelly CP, et al. Body mass index and the risk of obesity in coeliac disease treated with the gluten-free diet. Aliment Pharmacol Ther. 2012;35:723-729.
Diamanti A, Capriati T, Basso M, et al. Celiac disease and overweight in children: an update. Nutrients. 2014;6:207-220.
van der Pals M, Myléus A, Norström F, et al. Body mass index is not a reliable tool in predicting celiac disease in children. BMC Pediatr. 2014;14:165.
Aurangzeb B, Leach ST, Lemberg DA, Day AS. Nutritional status of children with coeliac disease. Acta Paediatr. 2010;99:1020-1025.
Venkatasubraman N, Telega G, Werlin SL. Obesity in pediatric celiac disease. J Pediatr Gastroenterol Nutr. 2010;51:295-297.
Reilly NR, Aguilar K, Hassid BG, et al. Celiac disease in normal-weight and overweight children: clinical features and growth outcomes following a gluten-free diet. J Pediatr Gastroenterol Nutr. 2011;53:528-531.
Cheng J, Brar PS, Lee AR, Green PH. Body mass index in celiac disease: beneficial effect of a gluten-free diet. J Clin Gastroenterol. 2010;44:267-271.
Amirikian K, Sansotta N, Guandalini S, Jericho H. Effects of the gluten-free diet on body mass indexes in pediatric celiac patients. J Pediatr Gastroenterol Nutr. 2019;68:360-363.
Valletta E, Fornaro M, Cipolli M, Conte S, Bissolo F, Danchielli C. Celiac disease and obesity: need for nutritional follow-up after diagnosis. Eur J Clin Nutr. 2010;64:1371-1372.
Brambilla P, Picca M, Dilillo D, et al. Changes of body mass index in celiac children on a gluten-free diet. Nutr Metab Cardiovasc Dis. 2013;23:177-182.
Husby S, Koletzko S, Korponay-Szabo IR, et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. J Pediatr Gastroenterol Nutr. 2012;54:136-160.
Marsh MN. Grains of truth: evolutionary changes in small intestinal mucosa in response to environmental antigen challenge. Gut. 1990;31:111-114.
Oberhuber G, Granditsch G, Vogelsang H. The histopathology of coeliac disease: time for a standardized report scheme for pathologists. Eur J Gastroenterol Hepatol. 1999;11:1185-1194.
Tambucci R, Quitadamo P, Ambrosi M, et al. Association between obesity/overweight and functional gastrointestinal disorders in children. J Pediatr Gastroenterol Nutr. 2019;68:517-520.
Galai T, Moran-Lev H, Cohen S, et al. Higher prevalence of obesity among children with functional abdominal pain disorders. BMC Pediatr. 2020;20:193.
Mariani P, Viti MG, Montouri M, et al. The gluten-free diet: a nutritional risk factor for adolescents with celiac disease? JPGN. 1998;27:519-523.
Johnston CS, Snyder D, Smith C. Commercially available gluten-free pastas elevate postprandial glycemia in comparison to conventional wheat pasta in healthy adults: a double-blind randomized crossover trial. Food Funct. 2017;8:3139-3144.
Ferrara P, Cicala M, Tiberi E, et al. High fat consumption in children with celiac disease. Acta Gastroenterol Belg. 2009;72:296-300.