A Novel Group of Promiscuous Podophages Infecting Diverse Gammaproteobacteria from River Communities Exhibits Dynamic Intergenus Host Adaptation.

bacteriophages environmental microbiology experimental evolution microbial ecology phage-bacterium interactions

Journal

mSystems
ISSN: 2379-5077
Titre abrégé: mSystems
Pays: United States
ID NLM: 101680636

Informations de publication

Date de publication:
02 Feb 2021
Historique:
entrez: 3 2 2021
pubmed: 4 2 2021
medline: 4 2 2021
Statut: epublish

Résumé

Phages are generally described as species specific or even strain specific, implying an inherent limitation for some to be maintained and spread in diverse bacterial communities. Moreover, phage isolation and host range determination rarely consider the phage ecological context, likely biasing our notion on phage specificity. Here we isolated and characterized a novel group of six promiscuous phages, named Atoyac, existing in rivers and sewage by using a diverse collection of over 600 bacteria retrieved from the same environments as potential hosts. These podophages isolated from different regions in Mexico display a remarkably broad host range, infecting bacteria from six genera:

Identifiants

pubmed: 33531404
pii: 6/1/e00773-20
doi: 10.1128/mSystems.00773-20
pmc: PMC7857530
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom

Commentaires et corrections

Type : ErratumIn

Informations de copyright

Copyright © 2021 Cazares et al.

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Auteurs

Daniel Cazares (D)

Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, Mexico cazares@comunidad.unam.mx vinuesa@ccg.unam.mx.

Adrian Cazares (A)

EMBL's European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Cambridge, United Kingdom.
Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.

Wendy Figueroa (W)

Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.

Gabriel Guarneros (G)

Departamento de Genética y Biología Molecular, CINVESTAV IPN, Mexico City, Mexico.

Robert A Edwards (RA)

FAME, Flinders University, Adelaide, SA, Australia.

Pablo Vinuesa (P)

Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, Mexico cazares@comunidad.unam.mx vinuesa@ccg.unam.mx.

Classifications MeSH