Zoonotic pathogen screening of striped field mice (Apodemus agrarius) from Austria.
Apodemus agrarius
Bartonella
Borrelia
Neoehrlichia mikurensis
Rickettsia
Dobrava-Belgrade orthohantavirus
Leptospira spp.
Journal
Transboundary and emerging diseases
ISSN: 1865-1682
Titre abrégé: Transbound Emerg Dis
Pays: Germany
ID NLM: 101319538
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
revised:
12
01
2021
received:
15
12
2019
accepted:
30
01
2021
pubmed:
4
2
2021
medline:
1
4
2022
entrez:
3
2
2021
Statut:
ppublish
Résumé
The striped field mouse (Apodemus agrarius) is known to carry several zoonotic pathogens, including Leptospira spp. and Dobrava-Belgrade orthohantavirus (DOBV). Since its first detection in 1996 in south-east Austria, the striped field mouse has further expanded its range in Austria. Here, we screened 35 striped field mice collected in an Austrian region near the Hungarian border for DOBV, Leptospira spp. and seven vector-borne pathogens. Hantavirus RT-PCR screening and DOBV IgG ELISA analysis led to the detection of two DOBV-positive striped field mice. The complete coding sequences of all three genome segments of both strains were determined by a combination of target enrichment and next-generation sequencing. Both complete coding S segment sequences clustered within the DOBV genotype Kurkino clade with the highest similarity to a sequence from Hungary. In one of 35 striped field mice, Leptospira borgpetersenii sequence type (ST) 146 was detected. Bartonella spp., Borrelia miyamotoi and Neoehrlichia mikurensis DNA was detected in four, one and two of 32 mice, respectively. Babesia, Anaplasma, Ehrlichia and Rickettsia specific DNA was not detected. Future investigations will have to determine the prevalence and invasion of these pathogens with the ongoing range expansion of the striped field mouse in Austria.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
886-890Subventions
Organisme : Bundesminsterium für Bildung und Forschung
ID : FKZ 01KI1730
Organisme : Bundesminsterium für Bildung und Forschung
ID : FKZ 01KI1721A
Organisme : Swiss National Science Foundation
ID : 31003A-176209
Pays : Switzerland
Informations de copyright
© 2021 The Authors. Transboundary and Emerging Diseases published by Wiley-VCH GmbH.
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