Risk of Aerosol Formation During High-Flow Nasal Cannula Treatment in Critically Ill Subjects.
ARDS
COVID-19
aerosol
high-flow nasal cannula
oxygen therapy
pneumonia
respiratory virus
Journal
Respiratory care
ISSN: 1943-3654
Titre abrégé: Respir Care
Pays: United States
ID NLM: 7510357
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
pubmed:
5
2
2021
medline:
1
6
2021
entrez:
4
2
2021
Statut:
ppublish
Résumé
There is a persistent concern over the risk of respiratory pathogen transmission, including SARS-CoV-2, via the formation of aerosols (ie, a suspension of microdroplets and residual microparticles after evaporation) generated during high-flow nasal cannula (HFNC) oxygen therapy in critically ill patients. This concern is fueled by limited available studies on this subject. In this study, we tested our hypothesis that HFNC treatment is not associated with increased aerosol formation as compared to conventional oxygen therapy. We used laser light scattering and a handheld particle counter to detect and quantify aerosols in healthy subjects and in adults with acute respiratory disease, including COVID-19, during HFNC or conventional oxygen therapy. The use of HFNC was not associated with increased formation of aerosols as compared to conventional oxygen therapy in both healthy subjects ( In line with scarce previous clinical and experimental findings, our results indicate that HFNC itself does not result in overall increased aerosol formation as compared to conventional oxygen therapy. This suggests there is no increased risk of respiratory pathogen transmission to health care workers during HFNC.
Sections du résumé
BACKGROUND
There is a persistent concern over the risk of respiratory pathogen transmission, including SARS-CoV-2, via the formation of aerosols (ie, a suspension of microdroplets and residual microparticles after evaporation) generated during high-flow nasal cannula (HFNC) oxygen therapy in critically ill patients. This concern is fueled by limited available studies on this subject. In this study, we tested our hypothesis that HFNC treatment is not associated with increased aerosol formation as compared to conventional oxygen therapy.
METHODS
We used laser light scattering and a handheld particle counter to detect and quantify aerosols in healthy subjects and in adults with acute respiratory disease, including COVID-19, during HFNC or conventional oxygen therapy.
RESULTS
The use of HFNC was not associated with increased formation of aerosols as compared to conventional oxygen therapy in both healthy subjects (
CONCLUSIONS
In line with scarce previous clinical and experimental findings, our results indicate that HFNC itself does not result in overall increased aerosol formation as compared to conventional oxygen therapy. This suggests there is no increased risk of respiratory pathogen transmission to health care workers during HFNC.
Identifiants
pubmed: 33536316
pii: respcare.08756
doi: 10.4187/respcare.08756
doi:
Substances chimiques
Aerosols
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
891-896Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2021 by Daedalus Enterprises.
Déclaration de conflit d'intérêts
The authors have disclosed no conflicts of interest.