The molecular basis of socially mediated phenotypic plasticity in a eusocial paper wasp.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
03 02 2021
03 02 2021
Historique:
received:
15
07
2020
accepted:
12
01
2021
entrez:
4
2
2021
pubmed:
5
2
2021
medline:
23
2
2021
Statut:
epublish
Résumé
Phenotypic plasticity, the ability to produce multiple phenotypes from a single genotype, represents an excellent model with which to examine the relationship between gene expression and phenotypes. Analyses of the molecular foundations of phenotypic plasticity are challenging, however, especially in the case of complex social phenotypes. Here we apply a machine learning approach to tackle this challenge by analyzing individual-level gene expression profiles of Polistes dominula paper wasps following the loss of a queen. We find that caste-associated gene expression profiles respond strongly to queen loss, and that this change is partly explained by attributes such as age but occurs even in individuals that appear phenotypically unaffected. These results demonstrate that large changes in gene expression may occur in the absence of outwardly detectable phenotypic changes, resulting here in a socially mediated de-differentiation of individuals at the transcriptomic level but not at the levels of ovarian development or behavior.
Identifiants
pubmed: 33536437
doi: 10.1038/s41467-021-21095-6
pii: 10.1038/s41467-021-21095-6
pmc: PMC7859208
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
775Subventions
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/R003882/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/S003681/1
Pays : United Kingdom
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