Reproducible abscopal effect in a patient with lung cancer who underwent whole-brain irradiation and atezolizumab administration.
abscopal effect
atezolizumab
lung cancer
whole-brain irradiation
Journal
Thoracic cancer
ISSN: 1759-7714
Titre abrégé: Thorac Cancer
Pays: Singapore
ID NLM: 101531441
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
received:
04
01
2021
revised:
18
01
2021
accepted:
18
01
2021
pubmed:
5
2
2021
medline:
20
11
2021
entrez:
4
2
2021
Statut:
ppublish
Résumé
Due to the emergence of immune checkpoint inhibitors, the abscopal effect has gained more attention. We report a case of extracranial abscopal effect after whole-brain irradiation therapy due to brain metastasis. After the initial abscopal effect was confirmed, a second abscopal effect was confirmed following radiation therapy for bone metastases. This case confirms the reproducibility of the abscopal effect. Moreover, the abscopal effect was not observed in metastatic lesions with low immunogenicity, even in the same patient.
Identifiants
pubmed: 33538129
doi: 10.1111/1759-7714.13875
pmc: PMC7952789
doi:
Substances chimiques
Antibodies, Monoclonal, Humanized
0
Antineoplastic Agents
0
atezolizumab
52CMI0WC3Y
Types de publication
Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
985-988Informations de copyright
© 2021 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd.
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