Epidemiology, Diagnosis, Staging and Multimodal Therapy of Esophageal and Gastric Tumors.

MALT lymphoma esophageal cancer gastric cancer gastrointestinal stromal tumor mucosal resection neuroendocrine tumor submucosal dissection

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
02 Feb 2021
Historique:
received: 16 12 2020
revised: 14 01 2021
accepted: 25 01 2021
entrez: 5 2 2021
pubmed: 6 2 2021
medline: 6 2 2021
Statut: epublish

Résumé

Gastric and esophageal tumors are diverse neoplasms that involve mucosal and submucosal tissue layers and include squamous cell carcinomas, adenocarcinomas, spindle cell neoplasms, neuroendocrine tumors, marginal B cell lymphomas, along with less common tumors. The worldwide burden of esophageal and gastric malignancies is significant, with esophageal and gastric cancer representing the ninth and fifth most common cancers, respectively. The approach to diagnosis and staging of these lesions is multimodal and includes a combination of gastrointestinal endoscopy, endoscopic ultrasound, and cross-sectional imaging. Likewise, therapy is multidisciplinary and combines therapeutic endoscopy, surgery, radiotherapy, and systemic chemotherapeutic tools. Future directions for diagnosis of esophageal and gastric malignancies are evolving rapidly and will involve advances in endoscopic and endosonographic techniques including tethered capsules, optical coherence tomography, along with targeted cytologic and serological analyses.

Identifiants

pubmed: 33540736
pii: cancers13030582
doi: 10.3390/cancers13030582
pmc: PMC7867245
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

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Auteurs

Donelle Cummings (D)

Division of Gastroenterology and Hepatology, Department of Medicine, New York Medical College, New York City Health and Hospitals Corporation-Metropolitan Hospital Center, 1901 First Avenue, New York, NY 10029, USA.

Joyce Wong (J)

Division of Surgery, Mid Atlantic Kaiser Permanente, 700 2nd St. NE, 6th Floor, Washington, DC 20002, USA.

Russell Palm (R)

Department of Radiation Oncology, Moffitt Cancer Center, 12902 USF Magnolia Drive, Tampa, FL 33612, USA.

Sarah Hoffe (S)

Department of Radiation Oncology, Moffitt Cancer Center, 12902 USF Magnolia Drive, Tampa, FL 33612, USA.

Khaldoun Almhanna (K)

Division of Hematology/Oncology, Lifespan Cancer Institute, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, 593 Eddy St, George 312, Providence, RI 02903, USA.

Shivakumar Vignesh (S)

Division of Gastroenterology and Hepatology, Department of Medicine, SUNY Downstate Health Sciences University, MSC 1196, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.

Classifications MeSH