Synthetic Biology Approaches To Enhance Microalgal Productivity.

carbon fixation microalgae mixotrophy photosynthesis synthetic biology

Journal

Trends in biotechnology
ISSN: 1879-3096
Titre abrégé: Trends Biotechnol
Pays: England
ID NLM: 8310903

Informations de publication

Date de publication:
10 2021
Historique:
received: 08 10 2020
revised: 22 12 2020
accepted: 29 12 2020
pubmed: 6 2 2021
medline: 16 10 2021
entrez: 5 2 2021
Statut: ppublish

Résumé

The major bottleneck in commercializing biofuels and other commodities produced by microalgae is the high cost associated with phototrophic cultivation. Improving microalgal productivities could be a solution to this problem. Synthetic biology methods have recently been used to engineer the downstream production pathways in several microalgal strains. However, engineering upstream photosynthetic and carbon fixation metabolism to enhance growth, productivity, and yield has barely been explored in microalgae. We describe strategies to improve the generation of reducing power from light, as well as to improve the assimilation of CO

Identifiants

pubmed: 33541719
pii: S0167-7799(21)00004-4
doi: 10.1016/j.tibtech.2020.12.010
pii:
doi:

Substances chimiques

Biofuels 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1019-1036

Informations de copyright

Copyright © 2021 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Interests The authors declare no conflicts of interest.

Auteurs

Mihris Ibnu Saleem Naduthodi (MIS)

Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands; Bioprocess Engineering, AlgaePARC, Wageningen University, Wageningen, The Netherlands.

Nico J Claassens (NJ)

Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands.

Sarah D'Adamo (S)

Bioprocess Engineering, AlgaePARC, Wageningen University, Wageningen, The Netherlands.

John van der Oost (J)

Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands.

Maria J Barbosa (MJ)

Bioprocess Engineering, AlgaePARC, Wageningen University, Wageningen, The Netherlands. Electronic address: maria.barbosa@wur.nl.

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Classifications MeSH