Pre-Exposure Prophylaxis for COVID-19 in Pregnant Women.

COVID-19 SARS-CoV-2 hydroxychloroquine pre-exposure prophylaxis pregnancy vaccine

Journal

International journal of general medicine
ISSN: 1178-7074
Titre abrégé: Int J Gen Med
Pays: New Zealand
ID NLM: 101515487

Informations de publication

Date de publication:
2021
Historique:
received: 03 12 2020
accepted: 13 01 2021
entrez: 5 2 2021
pubmed: 6 2 2021
medline: 6 2 2021
Statut: epublish

Résumé

Pregnant women are at higher risk for developing severe complications of COVID-19 including preterm delivery, respiratory failure, and death. Although vaccines to prevent COVID-19 are being developed, pregnant women are not included in the current COVID-19 vaccine trials and initially this population may not be eligible for COVID-19 vaccines due to lack of safety testing in pregnancy. As an alternate approach, we discuss the concept of pre-exposure prophylaxis (PrEP) using medications that are approved for use in pregnant women to prevent gestational problems and severe illness in this high-risk population. In particular, the use of hydroxychloroquine PrEP affords a safe and readily available means to avoid COVID-19 complications in pregnancy.

Identifiants

pubmed: 33542646
doi: 10.2147/IJGM.S295627
pii: 295627
pmc: PMC7851576
doi:

Types de publication

Journal Article

Langues

eng

Pagination

279-284

Informations de copyright

© 2021 Fesler and Stricker.

Déclaration de conflit d'intérêts

RBS is the owner of the Alan E. Beer Medical Center for Reproductive Immunology and reports no other potential conflicts of interest for this work. MCF has no conflicts of interest for this work to declare.

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Auteurs

Melissa C Fesler (MC)

Alan E. Beer Medical Center for Reproductive Immunology, Los Gatos, CA, USA.
Union Square Medical Associates, San Francisco, CA, USA.

Raphael B Stricker (RB)

Alan E. Beer Medical Center for Reproductive Immunology, Los Gatos, CA, USA.
Union Square Medical Associates, San Francisco, CA, USA.

Classifications MeSH