Effectiveness of oritavancin for management of skin and soft tissue infections in the emergency department: A case series.


Journal

The American journal of emergency medicine
ISSN: 1532-8171
Titre abrégé: Am J Emerg Med
Pays: United States
ID NLM: 8309942

Informations de publication

Date de publication:
05 2021
Historique:
received: 11 11 2020
revised: 18 01 2021
accepted: 20 01 2021
pubmed: 6 2 2021
medline: 22 6 2021
entrez: 5 2 2021
Statut: ppublish

Résumé

Skin and soft tissue infections, such as cellulitis, are commonly diagnosed in the emergency department and these patients are often admitted to the hospital for intravenous antibiotic therapy. Oritavancin is a novel antibiotic approved for the treatment of skin and soft tissue infections that is administered as a one-time infusion. While oritavancin has demonstrated comparable efficacy with multi-dose parenteral antibiotics in clinical trials and has been proposed as an alternative to admission for emergency department patients, there is a paucity of available real world effectiveness data. In this case series, we describe the characteristics and outcomes of ten patients with high-risk skin and soft tissue infections who received oritavancin and were discharged from the emergency department.

Identifiants

pubmed: 33545550
pii: S0735-6757(21)00053-X
doi: 10.1016/j.ajem.2021.01.050
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Lipoglycopeptides 0
oritavancin PUG62FRZ2E

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

77-80

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Drew Dretske (D)

Department of Pharmacy, University of Wisconsin Health; 600, Highland, Ave. Madison, WI 53792, USA. Electronic address: ddretske@uwhealth.org.

Lucas Schulz (L)

Department of Pharmacy, University of Wisconsin Health; 600, Highland, Ave. Madison, WI 53792, USA. Electronic address: lschulz2@uwhealth.org.

Erin Werner (E)

BerbeeWalsh Department of Emergency Medicine, University of Wisconsin-Madison School of Medicine and Public Health, 800 University Bay Drive, Suite 310, Madison, WI 53705, USA. Electronic address: ewerner@uwhealth.org.

Brian Sharp (B)

BerbeeWalsh Department of Emergency Medicine, University of Wisconsin-Madison School of Medicine and Public Health, 800 University Bay Drive, Suite 310, Madison, WI 53705, USA. Electronic address: bsharp@medicine.wisc.edu.

Michael Pulia (M)

BerbeeWalsh Department of Emergency Medicine, University of Wisconsin-Madison School of Medicine and Public Health, 800 University Bay Drive, Suite 310, Madison, WI 53705, USA. Electronic address: mspulia@medicine.wisc.edu.

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Classifications MeSH