Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell.


Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
02 2021
Historique:
received: 15 06 2020
accepted: 18 12 2020
entrez: 6 2 2021
pubmed: 7 2 2021
medline: 19 4 2022
Statut: epublish

Résumé

Neuroblastoma is a childhood cancer that resembles developmental stages of the neural crest. It is not established what developmental processes neuroblastoma cancer cells represent. Here, we sought to reveal the phenotype of neuroblastoma cancer cells by comparing cancer (

Identifiants

pubmed: 33547074
pii: 7/6/eabd3311
doi: 10.1126/sciadv.abd3311
pmc: PMC7864567
pii:
doi:

Substances chimiques

RNA, Messenger 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Medical Research Council
ID : MC_PC_17230
Pays : United Kingdom

Commentaires et corrections

Type : ErratumIn

Informations de copyright

Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).

Références

Stem Cell Reports. 2017 Jun 6;8(6):1714-1726
pubmed: 28506533
Children (Basel). 2018 Aug 31;5(9):
pubmed: 30200332
Nat Genet. 2013 Mar;45(3):279-84
pubmed: 23334666
Nat Methods. 2017 Mar;14(3):309-315
pubmed: 28114287
Proc Natl Acad Sci U S A. 1984 Aug;81(15):4940-4
pubmed: 6589638
Science. 1984 Dec 14;226(4680):1335-7
pubmed: 6505694
Nature. 2017 Oct 11;550(7675):204-213
pubmed: 29022597
Nat Biotechnol. 2018 Jun;36(5):411-420
pubmed: 29608179
Cell Syst. 2019 Apr 24;8(4):281-291.e9
pubmed: 30954476
J Am Soc Nephrol. 1993 Oct;4(4):976-85
pubmed: 8286719
Cell. 2019 Jun 13;177(7):1888-1902.e21
pubmed: 31178118
Genome Biol. 2006;7(9):R84
pubmed: 16989664
Annu Rev Physiol. 2001;63:193-213
pubmed: 11181954
Nature. 2020 Feb;578(7793):112-121
pubmed: 32025012
Nature. 2018 Aug;560(7719):494-498
pubmed: 30089906
Development. 2013 Nov;140(22):4522-32
pubmed: 24131628
J Stat Softw. 2010;33(1):1-22
pubmed: 20808728
Sci Data. 2018 Oct 30;5:180240
pubmed: 30375995
Front Mol Neurosci. 2019 Jan 25;12:6
pubmed: 30740044
Dev Neurobiol. 2016 Feb;76(2):137-49
pubmed: 25989220
Int J Oncol. 2008 Nov;33(5):985-91
pubmed: 18949361
Cold Spring Harb Perspect Med. 2013 Jan 01;3(1):a011643
pubmed: 23209159
Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16910-5
pubmed: 20837533
Bioinformatics. 2010 Mar 1;26(5):589-95
pubmed: 20080505
Nat Genet. 2017 Aug;49(8):1261-1266
pubmed: 28650485
Science. 2017 Jul 7;357(6346):
pubmed: 28684471
Paediatr Perinat Epidemiol. 2009 Mar;23(2):125-43
pubmed: 19159399
Curr Protoc Bioinformatics. 2016 Dec 8;56:15.9.1-15.9.17
pubmed: 27930809
Oncogene. 2005 Nov 24;24(53):7902-12
pubmed: 16103881
Nat Methods. 2017 Oct;14(10):979-982
pubmed: 28825705
Lancet Oncol. 2012 Mar;13(3):229-30
pubmed: 22381931
Dev Biol. 2018 Dec 1;444 Suppl 1:S25-S35
pubmed: 29454705
Gigascience. 2020 Dec 26;9(12):
pubmed: 33367645
Cancer Res. 2001 Sep 15;61(18):6892-8
pubmed: 11559566
Nat Commun. 2019 Apr 4;10(1):1530
pubmed: 30948783
J Bone Miner Res. 2008 Sep;23(9):1519-28
pubmed: 18410236
Nat Biotechnol. 2014 Sep;32(9):926-32
pubmed: 25150839
Front Oncol. 2020 Jul 07;10:1000
pubmed: 32733795
Bioinformatics. 2010 Jan 1;26(1):139-40
pubmed: 19910308
Bioinformatics. 2011 Nov 1;27(21):2987-93
pubmed: 21903627
Nat Rev Dis Primers. 2016 Nov 10;2:16078
pubmed: 27830764
Development. 1995 Dec;121(12):4045-55
pubmed: 8575305
Circ Res. 2007 Feb 2;100(2):174-90
pubmed: 17272819
Nature. 2015 Oct 1;526(7571):68-74
pubmed: 26432245
Nat Biotechnol. 2014 Apr;32(4):381-386
pubmed: 24658644
Cell Syst. 2016 Oct 26;3(4):385-394.e3
pubmed: 27693023
Am J Pathol. 1974 Aug;76(2):225-44
pubmed: 4843383
Nat Methods. 2009 Apr;6(4):291-5
pubmed: 19287394
Pediatr Dev Pathol. 2018 Jul-Aug;21(4):355-362
pubmed: 29067879
Oncotarget. 2017 Aug 4;8(42):72133-72146
pubmed: 29069774
EMBO J. 2002 Sep 16;21(18):4885-95
pubmed: 12234928
Science. 2019 Jun 07;364(6444):
pubmed: 31171666
Science. 2018 Aug 10;361(6402):594-599
pubmed: 30093597

Auteurs

Gerda Kildisiute (G)

Wellcome Sanger Institute, CB10 1SA Hinxton, UK.

Waleed M Kholosy (WM)

Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, Netherlands.

Matthew D Young (MD)

Wellcome Sanger Institute, CB10 1SA Hinxton, UK. my4@sanger.ac.uk k.straathof@ucl.ac.uk j.j.molenaar@prinsesmaximacentrum.nl sb31@sanger.ac.uk.

Kenny Roberts (K)

Wellcome Sanger Institute, CB10 1SA Hinxton, UK.

Rasa Elmentaite (R)

Wellcome Sanger Institute, CB10 1SA Hinxton, UK.

Sander R van Hooff (SR)

Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, Netherlands.

Clarissa N Pacyna (CN)

Wellcome Sanger Institute, CB10 1SA Hinxton, UK.

Eleonora Khabirova (E)

Wellcome Sanger Institute, CB10 1SA Hinxton, UK.

Alice Piapi (A)

UCL Great Ormond Street Institute of Child Health, WC1N 1EH London, UK.

Christine Thevanesan (C)

UCL Great Ormond Street Institute of Child Health, WC1N 1EH London, UK.

Eva Bugallo-Blanco (E)

UCL Great Ormond Street Institute of Child Health, WC1N 1EH London, UK.

Christina Burke (C)

UCL Great Ormond Street Institute of Child Health, WC1N 1EH London, UK.

Lira Mamanova (L)

Wellcome Sanger Institute, CB10 1SA Hinxton, UK.

Kaylee M Keller (KM)

Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, Netherlands.

Karin P S Langenberg-Ververgaert (KPS)

Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, Netherlands.

Philip Lijnzaad (P)

Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, Netherlands.

Thanasis Margaritis (T)

Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, Netherlands.

Frank C P Holstege (FCP)

Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, Netherlands.

Michelle L Tas (ML)

Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, Netherlands.

Marc H W A Wijnen (MHWA)

Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, Netherlands.

Max M van Noesel (MM)

Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, Netherlands.

Ignacio Del Valle (I)

UCL Great Ormond Street Institute of Child Health, WC1N 1EH London, UK.

Giuseppe Barone (G)

Great Ormond Street Hospital for Children (GOSH), NHS Foundation Trust, NIHR Great Ormond Street Hospital Biomedical Research Centre, WC1N 3JH London, UK.

Reinier van der Linden (R)

Hubrecht Institute, KNAW, 3584 CT Utrecht, Netherlands.

Catriona Duncan (C)

Great Ormond Street Hospital for Children (GOSH), NHS Foundation Trust, NIHR Great Ormond Street Hospital Biomedical Research Centre, WC1N 3JH London, UK.

John Anderson (J)

UCL Great Ormond Street Institute of Child Health, WC1N 1EH London, UK.
Great Ormond Street Hospital for Children (GOSH), NHS Foundation Trust, NIHR Great Ormond Street Hospital Biomedical Research Centre, WC1N 3JH London, UK.

John C Achermann (JC)

UCL Great Ormond Street Institute of Child Health, WC1N 1EH London, UK.

Muzlifah Haniffa (M)

Wellcome Sanger Institute, CB10 1SA Hinxton, UK.
Institute of Cellular Medicine, Newcastle University, NE2 4HH Newcastle upon Tyne, UK.
Department of Dermatology and NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals, NHS Foundation Trust, NE2 4LP Newcastle upon Tyne, UK.

Sarah A Teichmann (SA)

Wellcome Sanger Institute, CB10 1SA Hinxton, UK.

Dyanne Rampling (D)

Great Ormond Street Hospital for Children (GOSH), NHS Foundation Trust, NIHR Great Ormond Street Hospital Biomedical Research Centre, WC1N 3JH London, UK.

Neil J Sebire (NJ)

Great Ormond Street Hospital for Children (GOSH), NHS Foundation Trust, NIHR Great Ormond Street Hospital Biomedical Research Centre, WC1N 3JH London, UK.

Xiaoling He (X)

MRC-WT Cambridge Stem Cell Institute, University of Cambridge, CB2 0QQ Cambridge, UK.
Department of Clinical Neurosciences, University of Cambridge, CB2 0QQ Cambridge, UK.

Ronald R de Krijger (RR)

Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, Netherlands.
Department of Pathology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, Netherlands.

Roger A Barker (RA)

MRC-WT Cambridge Stem Cell Institute, University of Cambridge, CB2 0QQ Cambridge, UK.
Department of Clinical Neurosciences, University of Cambridge, CB2 0QQ Cambridge, UK.

Kerstin B Meyer (KB)

Wellcome Sanger Institute, CB10 1SA Hinxton, UK.

Omer Bayraktar (O)

Wellcome Sanger Institute, CB10 1SA Hinxton, UK.

Karin Straathof (K)

UCL Great Ormond Street Institute of Child Health, WC1N 1EH London, UK. my4@sanger.ac.uk k.straathof@ucl.ac.uk j.j.molenaar@prinsesmaximacentrum.nl sb31@sanger.ac.uk.
Great Ormond Street Hospital for Children (GOSH), NHS Foundation Trust, NIHR Great Ormond Street Hospital Biomedical Research Centre, WC1N 3JH London, UK.

Jan J Molenaar (JJ)

Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, Netherlands. my4@sanger.ac.uk k.straathof@ucl.ac.uk j.j.molenaar@prinsesmaximacentrum.nl sb31@sanger.ac.uk.

Sam Behjati (S)

Wellcome Sanger Institute, CB10 1SA Hinxton, UK. my4@sanger.ac.uk k.straathof@ucl.ac.uk j.j.molenaar@prinsesmaximacentrum.nl sb31@sanger.ac.uk.
Cambridge University Hospitals NHS Foundation Trust, CB2 0QQ Cambridge, UK.
Department of Paediatrics, University of Cambridge, CB2 0QQ Cambridge, UK.

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