Double-clip traction for colonic endoscopic submucosal dissection: a multicenter study of 599 consecutive cases (with video).


Journal

Gastrointestinal endoscopy
ISSN: 1097-6779
Titre abrégé: Gastrointest Endosc
Pays: United States
ID NLM: 0010505

Informations de publication

Date de publication:
08 2021
Historique:
received: 09 11 2020
accepted: 24 01 2021
pubmed: 7 2 2021
medline: 11 8 2021
entrez: 6 2 2021
Statut: ppublish

Résumé

Colonic endoscopic submucosal dissection (ESD) is particularly challenging and limited to a few expert centers. We recently conducted a pilot study on improvement of colonic ESD with systematic use of a countertraction device (double-clip traction with rubber band [DCT-ESD]). A French prospective multicenter study was conducted between March 2017 and September 2019, including all consecutive cases of naive colonic ESD. Since the first case of DCT-ESD in March 2017, all cases of colonic ESD have been performed using the DCT-ESD strategy in the 3 centers involved in the study. Five hundred ninety-nine lesions with a mean size of 53 mm were included in this study, resected by 5 operators in 3 centers. The en bloc, R0, and curative resection rates were 95.7%, 83.5%, and 81.1%, respectively. The adverse event rates were 4.9% for perforation and 4.2% for postprocedure bleeding. Between 2017 and 2019, the rates of R0 and curative resections increased significantly from 74.7% in 2017 to 88.4% in 2019 (P = .003) and from 72.6% in 2017 to 86.3% in 2019 (P = .004), respectively. Procedure duration and speed of resection were 62.4 minutes and 39.4 mm DCT-ESD is a safe and reproducible technique, with results comparable with those of the large Japanese teams with speed of resection twice as high as previously reported studies. The DCT strategy is promising, cheap, and seems to be reproducible. Physicians performing colonic ESD should be aware of this promising tool to improve their results in ESD.

Sections du résumé

BACKGROUND AND AIMS
Colonic endoscopic submucosal dissection (ESD) is particularly challenging and limited to a few expert centers. We recently conducted a pilot study on improvement of colonic ESD with systematic use of a countertraction device (double-clip traction with rubber band [DCT-ESD]).
METHODS
A French prospective multicenter study was conducted between March 2017 and September 2019, including all consecutive cases of naive colonic ESD. Since the first case of DCT-ESD in March 2017, all cases of colonic ESD have been performed using the DCT-ESD strategy in the 3 centers involved in the study.
RESULTS
Five hundred ninety-nine lesions with a mean size of 53 mm were included in this study, resected by 5 operators in 3 centers. The en bloc, R0, and curative resection rates were 95.7%, 83.5%, and 81.1%, respectively. The adverse event rates were 4.9% for perforation and 4.2% for postprocedure bleeding. Between 2017 and 2019, the rates of R0 and curative resections increased significantly from 74.7% in 2017 to 88.4% in 2019 (P = .003) and from 72.6% in 2017 to 86.3% in 2019 (P = .004), respectively. Procedure duration and speed of resection were 62.4 minutes and 39.4 mm
CONCLUSION
DCT-ESD is a safe and reproducible technique, with results comparable with those of the large Japanese teams with speed of resection twice as high as previously reported studies. The DCT strategy is promising, cheap, and seems to be reproducible. Physicians performing colonic ESD should be aware of this promising tool to improve their results in ESD.

Identifiants

pubmed: 33548280
pii: S0016-5107(21)00099-7
doi: 10.1016/j.gie.2021.01.036
pii:
doi:

Types de publication

Journal Article Multicenter Study Video-Audio Media

Langues

eng

Sous-ensembles de citation

IM

Pagination

333-343

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2021 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

Auteurs

Pierre Bordillon (P)

Service d'Hépato-gastro-entérologie, CHU Dupuytren, Limoges, France.

Mathieu Pioche (M)

Service d'Hépato-gastro-entérologie, CHU Edouard Herriot, Lyon, France.

Thimotée Wallenhorst (T)

Service d'Hépato-gastro-entérologie, CHU Pontchaillou, Rennes, France.

Jérôme Rivory (J)

Service d'Hépato-gastro-entérologie, CHU Edouard Herriot, Lyon, France.

Romain Legros (R)

Service d'Hépato-gastro-entérologie, CHU Dupuytren, Limoges, France.

Jérémie Albouys (J)

Service d'Hépato-gastro-entérologie, CHU Dupuytren, Limoges, France.

Hugo Lepetit (H)

Service d'Hépato-gastro-entérologie, CHU Dupuytren, Limoges, France.

Florian Rostain (F)

Service d'Hépato-gastro-entérologie, CHU Edouard Herriot, Lyon, France.

Martin Dahan (M)

Service d'Hépato-gastro-entérologie, CHU Dupuytren, Limoges, France.

Thierry Ponchon (T)

Service d'Hépato-gastro-entérologie, CHU Edouard Herriot, Lyon, France.

Denis Sautereau (D)

Service d'Hépato-gastro-entérologie, CHU Dupuytren, Limoges, France.

Véronique Loustaud-Ratti (V)

Service d'Hépato-gastro-entérologie, CHU Dupuytren, Limoges, France.

Sophie Geyl (S)

Service d'Hépato-gastro-entérologie, CHU Dupuytren, Limoges, France.

Jérémie Jacques (J)

Service d'Hépato-gastro-entérologie, CHU Dupuytren, Limoges, France.

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