Evacuation after the Great East Japan Earthquake is an independent factor associated with hyperuricemia: The Fukushima Health Management Survey.


Journal

Nutrition, metabolism, and cardiovascular diseases : NMCD
ISSN: 1590-3729
Titre abrégé: Nutr Metab Cardiovasc Dis
Pays: Netherlands
ID NLM: 9111474

Informations de publication

Date de publication:
09 04 2021
Historique:
received: 13 07 2020
revised: 25 11 2020
accepted: 11 12 2020
pubmed: 8 2 2021
medline: 7 4 2021
entrez: 7 2 2021
Statut: ppublish

Résumé

On March 11, 2011, the Great East Japan Earthquake occurred in Japan, with a nuclear accident subsequently occurring at the Fukushima Daiichi Nuclear Power Plant. The disaster forced many evacuees to change particular aspects of their lifestyles. This study assessed the association between evacuation and hyperuricemia based on the Fukushima Health Management Survey from a lifestyle and socio-psychological perspective. This cross-sectional study included 22,812 residents (9391 men and 13,297 women) who underwent both the Comprehensive Health Check and the Mental Health and Lifestyle Survey in fiscal year 2011. Associations between hyperuricemia and lifestyle- and disaster-related factors including evacuation were estimated using a logistic and liner regression analysis. With hyperuricemia defined as uric acid levels >7.0 mg/dL for men and >6.0 mg/dL for women, significant associations were observed between evacuation and hyperuricemia in men (the multivariate-adjusted odds ratio 1.20, 95% confidence interval, 1.05-1.36, p = 0.005), but not in women. In the multivariate-adjusted multiple liner regression analysis, evacuation had significant and positive associations with uric acid levels both in men (β = 0.084, p = 0.002) and women (β = 0.060, p < 0.001). Evacuation after a natural disaster is an independent factor associated with hyperuricemia.

Sections du résumé

BACKGROUND AND AIMS
On March 11, 2011, the Great East Japan Earthquake occurred in Japan, with a nuclear accident subsequently occurring at the Fukushima Daiichi Nuclear Power Plant. The disaster forced many evacuees to change particular aspects of their lifestyles. This study assessed the association between evacuation and hyperuricemia based on the Fukushima Health Management Survey from a lifestyle and socio-psychological perspective.
METHODS AND RESULTS
This cross-sectional study included 22,812 residents (9391 men and 13,297 women) who underwent both the Comprehensive Health Check and the Mental Health and Lifestyle Survey in fiscal year 2011. Associations between hyperuricemia and lifestyle- and disaster-related factors including evacuation were estimated using a logistic and liner regression analysis. With hyperuricemia defined as uric acid levels >7.0 mg/dL for men and >6.0 mg/dL for women, significant associations were observed between evacuation and hyperuricemia in men (the multivariate-adjusted odds ratio 1.20, 95% confidence interval, 1.05-1.36, p = 0.005), but not in women. In the multivariate-adjusted multiple liner regression analysis, evacuation had significant and positive associations with uric acid levels both in men (β = 0.084, p = 0.002) and women (β = 0.060, p < 0.001).
CONCLUSION
Evacuation after a natural disaster is an independent factor associated with hyperuricemia.

Identifiants

pubmed: 33549460
pii: S0939-4753(20)30525-1
doi: 10.1016/j.numecd.2020.12.016
pii:
doi:

Substances chimiques

Biomarkers 0
Uric Acid 268B43MJ25

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1177-1188

Informations de copyright

Copyright © 2021 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors have no conflict of interest to note.

Auteurs

Kazuya Honda (K)

Department of Nephrology and Hypertension, Fukushima Medical University School of Medicine, Fukushima, Japan; Department of Endocrinology, Metabolism, Diabetology, and Nephrology, Fukushima Medical University Aizu Medical Center, Aizuwakamatsu, Japan.

Kanako Okazaki (K)

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan; Preparing Section for New Faculty of Medical Science Fukushima Medical University, Fukushima, Japan.

Kenichi Tanaka (K)

Department of Nephrology and Hypertension, Fukushima Medical University School of Medicine, Fukushima, Japan. Electronic address: kennichi@fmu.ac.jp.

Junichiro J Kazama (JJ)

Department of Nephrology and Hypertension, Fukushima Medical University School of Medicine, Fukushima, Japan; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan.

Shigeatsu Hashimoto (S)

Department of Endocrinology, Metabolism, Diabetology, and Nephrology, Fukushima Medical University Aizu Medical Center, Aizuwakamatsu, Japan; Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan.

Tetsuya Ohira (T)

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan; Department of Epidemiology, Fukushima Medical University School of Medicine, Fukushima, Japan.

Akira Sakai (A)

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan; Department of Radiation Life Sciences, Fukushima Medical University School of Medicine, Fukushima, Japan.

Seiji Yasumura (S)

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan; Department of Public Health, Fukushima Medical University School of Medicine, Fukushima, Japan.

Masaharu Maeda (M)

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan; Department of Disaster Psychiatry, Fukushima Medical University School of Medicine, Fukushima, Japan.

Hirooki Yabe (H)

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan; Department of Neuropsychiatry, Fukushima Medical University School of Medicine, Fukushima, Japan.

Yuriko Suzuki (Y)

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan; Department of Mental Health Policy, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.

Mitsuaki Hosoya (M)

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan; Department of Pediatrics, Fukushima Medical University School of Medicine, Fukushima, Japan.

Atsushi Takahashi (A)

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan; Department of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.

Hironori Nakano (H)

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan; Department of Epidemiology, Fukushima Medical University School of Medicine, Fukushima, Japan.

Fumikazu Hayashi (F)

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan; Department of Epidemiology, Fukushima Medical University School of Medicine, Fukushima, Japan.

Masanori Nagao (M)

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan; Department of Epidemiology, Fukushima Medical University School of Medicine, Fukushima, Japan.

Hiromasa Ohira (H)

Department of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.

Michio Shimabukuro (M)

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan; Department of Diabetology Metabolism, and Endocrinology, Fukushima Medical University School of Medicine, Fukushima, Japan.

Hitoshi Ohto (H)

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan.

Kenji Kamiya (K)

Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima, Japan.

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