Obstetrics outcomes after complete and partial molar pregnancy: Review of the literature and meta-analysis.


Journal

European journal of obstetrics, gynecology, and reproductive biology
ISSN: 1872-7654
Titre abrégé: Eur J Obstet Gynecol Reprod Biol
Pays: Ireland
ID NLM: 0375672

Informations de publication

Date de publication:
Apr 2021
Historique:
received: 13 11 2020
revised: 19 01 2021
accepted: 25 01 2021
pubmed: 8 2 2021
medline: 15 5 2021
entrez: 7 2 2021
Statut: ppublish

Résumé

The hydatidiform mole is a rare gynecological disease rising from the trophoblastic. Post-molar pregnancies have an extremely variable course, varying from repeated abortions, stillbirths, preterm births, live births, or recurring in further molar pregnancies. Literature on obstetric outcomes following molar pregnancy is poor, often including monocentric studies, and with data collected from national databases. This review and meta-analysis aim to analyze the obstetric outcomes after conservative management of complete (CHM) and partial (PHM) molar pregnancies. The meta-analysis was performed following the Meta-analysis Of Observational Studies in Epidemiology (MOOSE) and the preferred reporting items for systematic reviews and meta-analyses statement (PRISMA). Six studies met the inclusion. Of the total 25,222 patients, 13,129 complete (52.1 %) and 12,093 partial (47.9 %) molar pregnancies were included. Live births rate after CHM was statistically higher (p = 0.002) compared to the live births after PHM (53.6 % vs. 51.0 %, 3266 vs. 1807 cases, respectively). Studies showed heterogeneity I

Identifiants

pubmed: 33550107
pii: S0301-2115(21)00065-8
doi: 10.1016/j.ejogrb.2021.01.051
pii:
doi:

Types de publication

Journal Article Meta-Analysis Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

18-25

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors report no declarations of interest.

Auteurs

Vito Andrea Capozzi (VA)

Department of Gynecology and Obstetrics, University of Parma, Via Gramsci, 43125, Parma, Italy. Electronic address: capozzivitoandrea@gmail.com.

Diana Butera (D)

Department of Gynecology and Obstetrics, University of Parma, Via Gramsci, 43125, Parma, Italy.

Giulia Armano (G)

Department of Gynecology and Obstetrics, University of Parma, Via Gramsci, 43125, Parma, Italy.

Luciano Monfardini (L)

Department of Gynecology and Obstetrics, University of Parma, Via Gramsci, 43125, Parma, Italy.

Michela Gaiano (M)

Department of Gynecology and Obstetrics, University of Parma, Via Gramsci, 43125, Parma, Italy.

Giulia Gambino (G)

Department of Gynecology and Obstetrics, University of Parma, Via Gramsci, 43125, Parma, Italy.

Giulio Sozzi (G)

Department of Gynecologic Oncology, University of Palermo, Piazzale N. Leotta, 90139, Palermo, Italy.

Carla Merisio (C)

Department of Gynecology and Obstetrics, University of Parma, Via Gramsci, 43125, Parma, Italy.

Roberto Berretta (R)

Department of Gynecology and Obstetrics, University of Parma, Via Gramsci, 43125, Parma, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH