Oral squamous cell carcinoma may originate from bone marrow-derived stem cells.
bone marrow derived stem cells
clustering analysis
fluorescence in-situ hybridization analysis
hematopoietic stem cell transplantation
mesenchymal stem cells
microarray analysis
oral squamous cell carcinoma
sex chromosome
Journal
Oncology letters
ISSN: 1792-1074
Titre abrégé: Oncol Lett
Pays: Greece
ID NLM: 101531236
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
16
07
2020
accepted:
21
10
2020
entrez:
8
2
2021
pubmed:
9
2
2021
medline:
9
2
2021
Statut:
ppublish
Résumé
Molecules that demonstrate a clear association with the aggressiveness of oral squamous cell carcinoma (OSCC) have not yet been identified. The current study hypothesized that tumor cells in OSCC have three different origins: Epithelial stem cells, oral tissue stem cells from the salivary gland and bone marrow (BM) stem cells. It was also hypothesized that carcinomas derived from less-differentiated stem cells have a greater malignancy. In the present study, sex chromosome analysis by fluorescence
Identifiants
pubmed: 33552287
doi: 10.3892/ol.2021.12431
pii: OL-0-0-12431
pmc: PMC7798092
doi:
Types de publication
Journal Article
Langues
eng
Pagination
170Informations de copyright
Copyright: © Hasegawa et al.
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