An Ophthalmic Insight into Novel Coronavirus 2019 Disease: A Comprehensive Review of the Ocular Manifestations and Clinical Hazards.
Conjunctivitis
Contact lens
Novel coronavirus 2019
Ocular transmission
Retina
Severe acute respiratory syndrome coronavirus-2
Tear
Journal
Journal of current ophthalmology
ISSN: 2452-2325
Titre abrégé: J Curr Ophthalmol
Pays: India
ID NLM: 101678509
Informations de publication
Date de publication:
Historique:
received:
29
06
2020
revised:
26
07
2020
accepted:
05
10
2020
entrez:
8
2
2021
pubmed:
9
2
2021
medline:
9
2
2021
Statut:
epublish
Résumé
To discuss the ocular manifestations provoked by novel coronavirus 2019 (COVID-19) disease in humans, the natural history of the disease in the eye, and its treatment. We designed a narrative review of the ocular manifestations of COVID-19 based on the literature published till July 30, 2020. The databases were PubMed, Scopus, Cochrane Library, Google Scholar, and ScienceDirect. The inclusion criteria were (1) all types of clinical studies and (2) the topic was COVID-19 and its association to the eye regarding the current guidelines. From 168 abstracts screened, 61 papers fully filled the inclusion criteria after the full-text screening. The 61 records include 13 case reports, 17 prospective (case series or cross-sectional) studies, 8 retrospective studies, 12 literature reviews (one systematic review), and 11 letters to the editor. The majority of the papers agreed that ophthalmic manifestations due to COVID-19 were few and rarely encountered. The main ocular pathology seemed to be conjunctivitis, where the viral polymerase chain reaction also happened to be most detectable. Posterior segment or neuro-ophthalmic manifestations were scarce. Viral genome detection in the eye as well as viral portal of entry to the globe is still vague. The exact incidence of ocular manifestations in COVID-19 disease is uncertain. Conjunctivitis is the most prevalent ocular manifestation. It is still a debate whether the eye is a portal of entry for infection.
Identifiants
pubmed: 33553832
doi: 10.4103/JOCO.JOCO_255_20
pii: JCO-32-315
pmc: PMC7861109
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
315-328Informations de copyright
Copyright: © 2020 Journal of Current Ophthalmology.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
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