New Compartmental Reading Method for MRI Enables Accurate Localization of Cholesteatomas With High Sensitivity and Specificity.
Journal
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
ISSN: 1537-4505
Titre abrégé: Otol Neurotol
Pays: United States
ID NLM: 100961504
Informations de publication
Date de publication:
01 03 2021
01 03 2021
Historique:
entrez:
8
2
2021
pubmed:
9
2
2021
medline:
22
4
2021
Statut:
ppublish
Résumé
Cholesteatoma is an inflammatory disease, frequently observed in childrens and young adults, with a risk of relapse or recurrence. The few studies which analyzed cholesteatoma localization on magnetic resonance imaging (MRI) usually merged CT-MR images or relied on their authors' anatomical knowledge. We propose a compartmental reading method of the compartments of the middle ear cavity for an accurate localization of cholesteatomas on MR images alone. Our method uses easily recognizable anatomical landmarks, seen on both computed tomography (CT) and MRI, to delimit the middle ear compartments (epitympanum, mesotympanum, hypotympanum, retrotympanum, protympanum, antrum-mastoid cavity). We first tested it on 50 patients on non-enhanced temporal bone CT. Then, we evaluated its performances for the localization of cholesteatomas on MRI, compared with surgery on 31 patients (validation cohort). The selected anatomical landmarks that delimited the middle ear compartments were applicable in 98 to 100% of the cases. In the validation cohort, we were able to accurately localize the cholesteatoma on MRI in 83% of the cases (n = 26) with high sensitivity (95.7%) and specificity (98.6%). With our compartmental reading method, based on the recognition of well-known anatomical landmarks to differentiate the compartments of the middle ear cavity on MRI, we were able to accurately localize the cholesteatoma with high (>90%) sensitivity and specificity. Such landmarks are widely applicable and only require limited learning time based on key images. Accurate localization of the cholesteatoma is useful for the choice of surgical approach.
Identifiants
pubmed: 33555752
doi: 10.1097/MAO.0000000000002999
pii: 00129492-202103000-00020
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
431-437Informations de copyright
Copyright © 2021, Otology & Neurotology, Inc.
Déclaration de conflit d'intérêts
The authors disclose no conflicts of interest.
Références
Haginomori SI, Takamaki A, Nonaka R, Takenaka H. Residual cholesteatoma: incidence and localization in canal wall down tympanoplasty with soft-wall reconstruction. Arch Otolaryngol Head Neck Surg 2008; 134:652–657.
Gaillardin L, Lescanne E, Morinière S, Cottier JP, Robier A. Residual cholesteatoma: prevalence and location. Follow-up strategy in adults. Eur Ann Otorhinolaryngol Head Neck Dis 2012; 129:136–140.
Preciado DA. Biology of cholesteatoma: special considerations in pediatric patients. Int J Pediatr Otorhinolaryngol 2012; 76:319–321.
Ayache D, Darrouzet V, Dubrulle F, et al. Imaging of non-operated cholesteatoma: clinical practice guidelines. Eur Ann Otorhinolaryngol Head Neck Dis 2012; 129:148–152.
De Foer B, Vercruysse JP, Bernaerts A, et al. Detection of postoperative residual cholesteatoma with non-echo-planar diffusion-weighted magnetic resonance imaging. Otol Neurotol 2008; 29:513–517.
Jindal M, Riskalla A, Jiang D, Connor S, O’Connor AF. A systematic review of diffusion-weighted magnetic resonance imaging in the assessment of postoperative cholesteatoma. Otol Neurotol 2011; 32:1243–1249.
De Foer B, Vercruysse JP, Bernaerts A, et al. Middle ear cholesteatoma: non–echo-planar diffusion-weighted MR imaging versus delayed gadolinium-enhanced T1-weighted MR imaging–value in detection. Radiology 2010; 255:866–872.
Pennanéach A, Garetier M, Ollivier M, Ognard J, Marianowski R, Meriot P. Diagnostic accuracy of diffusion-weighted MR imaging versus delayed gadolinium enhanced T1-weighted imaging in middle ear recurrent cholesteatoma: a retrospective study of 39 patients. J Neuroradiol 2016; 43:148–154.
Lingam RK, Khatri P, Hughes J, Singh A. Apparent diffusion coefficients for detection of postoperative middle ear cholesteatoma on non–echo-planar diffusion-weighted Images. Radiology 2013; 269:504–510.
Thiriat S, Riehm S, Kremer S, Martin E, Veillon F. Apparent diffusion coefficient values of middle ear cholesteatoma differ from abscess and cholesteatoma admixed infection. Am J Neuroradiol 2009; 30:1123–1126.
Özgen B, Bulut E, Dolgun A, Bajin MD, Sennaroğlu L. Accuracy of turbo spin-echo diffusion-weighted imaging signal intensity measurements for the diagnosis of cholesteatoma. Diagn Interv Radiol 2017; 23:300–306.
Huins CT, Singh A, Lingam RK, Kalan A. Detecting cholesteatoma with non-echo planar (HASTE) diffusion-weighted magnetic resonance imaging. Otolaryngol Head Neck Surg 2010; 143:141–146.
Pizzini FB, Barbieri F, Beltramello A, Alessandrini F, Fiorino F. HASTE diffusion-weighted 3-Tesla magnetic resonance imaging in the diagnosis of primary and relapsing cholesteatoma. Otol Neurotol 2010; 31:596–602.
Akkari M, Gabrillargues J, Saroul N, et al. Contribution of magnetic resonance imaging to the diagnosis of middle ear cholesteatoma: analysis of a series of 97 cases. Eur Ann Otorhinolaryngol Head Neck Dis 2014; 131:153–158.
Khemani S, Lingam RK, Kalan A, Singh A. The value of non-echo planar HASTE diffusion-weighted MR imaging in the detection, localization and prediction of extent of postoperative cholesteatoma. Clin Otolaryngol 2011; 36:306–312.
Migirov L, Wolf M, Greenberg G, Eyal A. Non-EPI DW MRI in planning the surgical approach to primary and recurrent cholesteatoma. Otol Neurotol 2014; 35:121–125.
Karandikar A, Loke SC, Goh J, Yeo SB, Tan TY. Evaluation of cholesteatoma: our experience with DW propeller imaging. Acta Radiol 2015; 56:1108–1112.
Niu Y, Wang Z, Liu Y, et al. Radiation dose to the lens using different temporal bone CT scanning protocols. American Journal of Neuroradiology 2010; 31:226–229.
Potsic WP, Korman SB, Samadi DS, Wetmore RF. Congenital cholesteatoma: 20 years’ experience at The Children's Hospital of Philadelphia. Otolaryngol Head Neck Surg 2002; 126:409–414.
Dexian Tan A, Ng JH, Lim SA, Low DYM, Yuen HW. Classification of temporal bone pneumatization on high-resolution computed tomography: prevalence patterns and implications. Otolaryngol Head Neck Surg 2018; 159:743–749.
Gristwood RE, Venables WN. Growth rate and recurrence of residual epidermoid cholesteatoma after tympanoplasty. Clin Otolaryngol Allied Sci 1976; 1:169–182.
Songu M, Altay C, Onal K, et al. Correlation of computed tomography, echo-planar diffusion-weighted magnetic resonance imaging and surgical outcomes in middle ear cholesteatoma. Acta Otolaryngol 2015; 135:776–780.
Velthuis S, Van Everdingen KJ, Quak JJ, Colnot DR. The value of non echo planar, diffusion-weighted magnetic resonance imaging for the detection of residual or recurrent middle-ear cholesteatoma. J Laryngol Otol 2014; 128:599–603.