Squamous cell carcinoma at the site of ileo-anal pouch in Crohn's disease.
Crohn's disease
oncology
surgery
Journal
BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291
Informations de publication
Date de publication:
08 Feb 2021
08 Feb 2021
Historique:
entrez:
9
2
2021
pubmed:
10
2
2021
medline:
23
2
2021
Statut:
epublish
Résumé
Few cases of pouch-related cancers have been reported in inflammatory bowel disease, and squamous cell carcinoma (SCC) is very rare. We have reviewed the published literature searching the online databases PubMed and Medline. Since 1979, there have been eight cases of SCC developing after restorative proctocolectomy in ulcerative colitis. To date, there have been no reported cases of SCC of the ileo-anal pouch in Crohn's disease. We present the case of a 59-year-old woman who underwent colectomy with ileal pouch-anal anastomosis for Crohn's disease during the 1990s. The patient was noted to be anaemic and was experiencing significant weight loss with poor pouch function in 2019. Endoscopy with histology and radiological investigation revealed the presence of SCC of the pouch. This was subsequently treated with surgical therapy and chemoradiotherapy.
Identifiants
pubmed: 33558378
pii: 14/2/e237438
doi: 10.1136/bcr-2020-237438
pmc: PMC7872916
pii:
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
Références
Clin Transl Gastroenterol. 2016 Mar 03;7:e148
pubmed: 26938479
Dis Colon Rectum. 2005 Aug;48(8):1542-9
pubmed: 15937625
Dis Colon Rectum. 2005 May;48(5):1086-9
pubmed: 15933895
J Crohns Colitis. 2014 Oct;8(10):1261-6
pubmed: 24662397
Lancet. 1996 Mar 30;347(9005):854-7
pubmed: 8622390
Br Med J. 1978 Jul 8;2(6130):85-8
pubmed: 667572
Dis Colon Rectum. 2001 Jun;44(6):769-78
pubmed: 11391134
J Crohns Colitis. 2018 Jan 05;12(1):57-62
pubmed: 28981638
World J Gastroenterol. 2014 Aug 7;20(29):9872-81
pubmed: 25110418
J Crohns Colitis. 2019 May 27;13(6):735-743
pubmed: 30590513
Case Rep Oncol. 2017 Jan 27;10(1):112-122
pubmed: 28203173
Cancer. 2011 Jul 15;117(14):3081-92
pubmed: 21264836
Colorectal Dis. 2011 Sep;13(9):e314-5
pubmed: 20969710
Colorectal Dis. 2010 Sep;12(9):945-6
pubmed: 19906057
Gut. 1998 Sep;43(3):303-4
pubmed: 9863466
Gut. 2010 May;59(5):666-89
pubmed: 20427401
Dis Colon Rectum. 2014 Jan;57(1):76-82
pubmed: 24316949
Dis Colon Rectum. 2004 Nov;47(11):1808-15
pubmed: 15622572
J Crohns Colitis. 2018 Jan 5;12(1):1-16
pubmed: 28498901
World J Gastroenterol. 2016 Jan 21;22(3):961-73
pubmed: 26811640