Off-Target Stoichiometric Binding Identified from Toxicogenomics Explains Why Some Species Are More Sensitive than Others to a Widely Used Neonicotinoid.


Journal

Environmental science & technology
ISSN: 1520-5851
Titre abrégé: Environ Sci Technol
Pays: United States
ID NLM: 0213155

Informations de publication

Date de publication:
02 03 2021
Historique:
pubmed: 10 2 2021
medline: 24 4 2021
entrez: 9 2 2021
Statut: ppublish

Résumé

Neonicotinoids are currently licensed for use in 120 countries, making accurate nontarget species sensitivity predictions critical. Unfortunately, such predictions are fraught with uncertainty, as sensitivity is extrapolated from only a few test species and neonicotinoid sensitivities can differ greatly between closely related taxa. Combining classical toxicology with

Identifiants

pubmed: 33559465
doi: 10.1021/acs.est.0c05125
doi:

Substances chimiques

Insecticides 0
Neonicotinoids 0
Nitro Compounds 0
Receptors, Nicotinic 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3059-3069

Auteurs

Stephen Short (S)

UK Centre for Ecology & Hydrology, Maclean Building, Crowmarsh Gifford, Wallingford, Oxfordshire OX10 8BB, United Kingdom.
Cardiff School of Biosciences, BIOSI 1, University of Cardiff, P.O. Box 915, Cardiff, CF10 3TL, United Kingdom.

Alex Robinson (A)

UK Centre for Ecology & Hydrology, Maclean Building, Crowmarsh Gifford, Wallingford, Oxfordshire OX10 8BB, United Kingdom.

Elma Lahive (E)

UK Centre for Ecology & Hydrology, Maclean Building, Crowmarsh Gifford, Wallingford, Oxfordshire OX10 8BB, United Kingdom.

Amaia Green Etxabe (A)

UK Centre for Ecology & Hydrology, Maclean Building, Crowmarsh Gifford, Wallingford, Oxfordshire OX10 8BB, United Kingdom.

Szabolcs Hernádi (S)

Cardiff School of Biosciences, BIOSI 1, University of Cardiff, P.O. Box 915, Cardiff, CF10 3TL, United Kingdom.

M Glória Pereira (MG)

UK Centre for Ecology and Hydrology, Library Avenue, Bailrigg, Lancaster LA1 4AP, United Kingdom.

Peter Kille (P)

Cardiff School of Biosciences, BIOSI 1, University of Cardiff, P.O. Box 915, Cardiff, CF10 3TL, United Kingdom.

David J Spurgeon (DJ)

UK Centre for Ecology & Hydrology, Maclean Building, Crowmarsh Gifford, Wallingford, Oxfordshire OX10 8BB, United Kingdom.

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Classifications MeSH