Heterogeneity of murine periosteum progenitors involved in fracture healing.

alpha smooth muscle actin fracture mouse osteoblast pdgfra periosteum regenerative medicine skeletal stem cell stem cells

Journal

eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614

Informations de publication

Date de publication:
09 02 2021
Historique:
received: 04 05 2020
accepted: 08 02 2021
pubmed: 10 2 2021
medline: 1 2 2022
entrez: 9 2 2021
Statut: epublish

Résumé

The periosteum is the major source of cells involved in fracture healing. We sought to characterize progenitor cells and their contribution to bone fracture healing. The periosteum is highly enriched with progenitor cells, including Sca1

Identifiants

pubmed: 33560227
doi: 10.7554/eLife.58534
pii: 58534
pmc: PMC7906599
doi:
pii:

Banques de données

GEO
['GSE165846']

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIAMS NIH HHS
ID : R01 AR055607
Pays : United States
Organisme : NIAMS NIH HHS
ID : R01 AR070813
Pays : United States

Informations de copyright

© 2021, Matthews et al.

Déclaration de conflit d'intérêts

BM, SN, FS, JF, YC, EB, DG, IK No competing interests declared

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Auteurs

Brya G Matthews (BG)

Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.
Department of Reconstructive Sciences, UConn Health, Farmington, United States.

Sanja Novak (S)

Department of Reconstructive Sciences, UConn Health, Farmington, United States.

Francesca V Sbrana (FV)

Department of Reconstructive Sciences, UConn Health, Farmington, United States.

Jessica L Funnell (JL)

Department of Reconstructive Sciences, UConn Health, Farmington, United States.

Ye Cao (Y)

Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.

Emma J Buckels (EJ)

Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.

Danka Grcevic (D)

Department of Physiology and Immunology, University of Zagreb, Zagreb, Croatia.
Croatian Intitute for Brain Research, University of Zagreb, Zagreb, Croatia.

Ivo Kalajzic (I)

Department of Reconstructive Sciences, UConn Health, Farmington, United States.

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Classifications MeSH