Consensus recommendations for MRI and PET imaging of primary central nervous system lymphoma: guideline statement from the International Primary CNS Lymphoma Collaborative Group (IPCG).


Journal

Neuro-oncology
ISSN: 1523-5866
Titre abrégé: Neuro Oncol
Pays: England
ID NLM: 100887420

Informations de publication

Date de publication:
01 07 2021
Historique:
pubmed: 10 2 2021
medline: 5 8 2021
entrez: 9 2 2021
Statut: ppublish

Résumé

Advanced molecular and pathophysiologic characterization of primary central nervous system lymphoma (PCNSL) has revealed insights into promising targeted therapeutic approaches. Medical imaging plays a fundamental role in PCNSL diagnosis, staging, and response assessment. Institutional imaging variation and inconsistent clinical trial reporting diminishes the reliability and reproducibility of clinical response assessment. In this context, we aimed to: (1) critically review the use of advanced positron emission tomography (PET) and magnetic resonance imaging (MRI) in the setting of PCNSL; (2) provide results from an international survey of clinical sites describing the current practices for routine and advanced imaging, and (3) provide biologically based recommendations from the International PCNSL Collaborative Group (IPCG) on adaptation of standardized imaging practices. The IPCG provides PET and MRI consensus recommendations built upon previous recommendations for standardized brain tumor imaging protocols (BTIP) in primary and metastatic disease. A biologically integrated approach is provided to addresses the unique challenges associated with the imaging assessment of PCNSL. Detailed imaging parameters facilitate the adoption of these recommendations by researchers and clinicians. To enhance clinical feasibility, we have developed both "ideal" and "minimum standard" protocols at 3T and 1.5T MR systems that will facilitate widespread adoption.

Identifiants

pubmed: 33560416
pii: 6131740
doi: 10.1093/neuonc/noab020
pmc: PMC8248856
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1056-1071

Subventions

Organisme : NCI NIH HHS
ID : U01 CA220378
Pays : United States
Organisme : NINDS NIH HHS
ID : R21 NS082609
Pays : United States
Organisme : NCI NIH HHS
ID : L30 CA220897
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA239462
Pays : United States
Organisme : NCI NIH HHS
ID : P50 CA211015
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA139083
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA221938
Pays : United States
Organisme : EPA
ID : EP-C-15-003
Pays : United States
Organisme : NCI NIH HHS
ID : K08 CA237809
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA158079
Pays : United States
Organisme : NCI NIH HHS
ID : R21 CA223757
Pays : United States

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press on behalf of the Society for Neuro-Oncology.

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Auteurs

Ramon F Barajas (RF)

Department of Radiology, Neuroradiology Section, Oregon Health & Science University, Portland Oregon, USA.
Advanced Imaging Research Center, Oregon Health & Science University, Portland, Oregon, USA.
Knight Cancer Institute Translational Oncology Program, Oregon Health & Science University, Portland, Oregon, USA.

Letterio S Politi (LS)

Humanitas University and Humanitas Research and Clinical Center - IRCCS, Milan, Italy.
Boston Children's Hospital, Boston, Massachusetts, USA.

Nicoletta Anzalone (N)

Neuroradiology Unit, IRCCS San Raffaele Hospital and Vita-Salute University, Milan, Italy.

Heiko Schöder (H)

Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

Christopher P Fox (CP)

Department of Clinical Haematology, Nottingham University Hospitals NHS Trust, School of Medicine, University of Nottingham, Nottingham, UK.

Jerrold L Boxerman (JL)

Department of Diagnostic Imaging, Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA.

Timothy J Kaufmann (TJ)

Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.

C Chad Quarles (CC)

Department of Neuroimaging Research & Barrow Neuroimaging Innovation Center, Barrow Neurological Institute, Phoenix, Arizona, USA.

Benjamin M Ellingson (BM)

UCLA Brain Tumor Imaging Laboratory (BTIL), Departments of Radiological Sciences and Psychiatry, David Geffen School of Medicine, University of California - Los Angeles, Los Angeles, California, USA.
Departments of Radiological Sciences, Psychiatry, and Biobehavioral Sciences, David Geffen School of Medicine, University of California - Los Angeles, Los Angeles, California, USA.

Dorothee Auer (D)

Versus Arthritis Pain Centre, University of Nottingham, Nottingham, UK.
NIHR Nottingham Biomedical Research Centre, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
Sir Peter Mansfield Imaging Centre, School of Medicine, University of Nottingham, Nottingham, UK.

Ovidiu C Andronesi (OC)

A. A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA.

Andres J M Ferreri (AJM)

Lymphoma Unit, Department of Onco-Hematology, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Maciej M Mrugala (MM)

Department of Medicine, Division of Hematology and Oncology, Mayo Clinic Cancer Center, Phoenix, Arizona, USA.
Department of Neurology, Mayo Clinic, Phoenix, Arizona, USA.

Christian Grommes (C)

Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Department of Neurology, Weill Cornell Medical School, New York, New York, USA.

Edward A Neuwelt (EA)

Blood-Brain Barrier Program, Oregon Health & Science University, Portland, Oregon, USA.
Department of Neurology, Oregon Health & Science University, Portland, Oregon, USA.
Department of Neurological Surgery, Oregon Health & Science University, Portland, Oregon, USA.
Portland Veterans Affairs Medical Center, Portland, Oregon, USA.

Prakash Ambady (P)

Blood-Brain Barrier Program, Oregon Health & Science University, Portland, Oregon, USA.
Department of Neurology, Oregon Health & Science University, Portland, Oregon, USA.

James L Rubenstein (JL)

Division of Hematology/Oncology, University of California, San Francisco, California, USA.
Department of Medicine, University of California, San Francisco, California, USA.
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA.

Gerald Illerhaus (G)

Clinic of Hematology, Oncology and Palliative Care, Klinikum Stuttgart, Stuttgart, Germany.

Motoo Nagane (M)

Department of Neurosurgery, Kyorin University Faculty of Medicine, Tokyo, Japan.

Tracy T Batchelor (TT)

Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Leland S Hu (LS)

Department of Radiology, Neuroradiology Division, Mayo Clinic, Phoenix, Arizona, USA.

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