Interhemispheric transfer of working memories.

Animals Female Functional Laterality / physiology Macaca mulatta Male Memory, Short-Term / physiology Prefrontal Cortex / physiology Visual Perception / physiology
cognition interhemispheric neural synchrony prefrontal cortex working memory

Journal

Neuron
ISSN: 1097-4199
Titre abrégé: Neuron
Pays: United States
ID NLM: 8809320

Informations de publication

Date de publication:
17 03 2021
Historique:
received: 13 08 2020
revised: 17 12 2020
accepted: 14 01 2021
pubmed: 10 2 2021
medline: 27 3 2021
entrez: 9 2 2021
Statut: ppublish

Résumé

Visual working memory (WM) storage is largely independent between the left and right visual hemifields/cerebral hemispheres, yet somehow WM feels seamless. We studied how WM is integrated across hemifields by recording neural activity bilaterally from lateral prefrontal cortex. An instructed saccade during the WM delay shifted the remembered location from one hemifield to the other. Before the shift, spike rates and oscillatory power showed clear signatures of memory laterality. After the shift, the lateralization inverted, consistent with transfer of the memory trace from one hemisphere to the other. Transferred traces initially used different neural ensembles from feedforward-induced ones, but they converged at the end of the delay. Around the time of transfer, synchrony between the two prefrontal hemispheres peaked in theta and beta frequencies, with a directionality consistent with memory trace transfer. This illustrates how dynamics between the two cortical hemispheres can stitch together WM traces across visual hemifields.

Identifiants

DOI: 10.1016/j.neuron.2021.01.016 PMID: 33561399 PMC: PMC9134350
pubmed: 33561399
pii: S0896-6273(21)00038-6
doi: 10.1016/j.neuron.2021.01.016
pmc: PMC9134350
mid: NIHMS1808824
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

1055-1066.e4

Subventions

Organisme : NIMH NIH HHS
ID : R37 MH087027
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007753
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2021 The Author(s). Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Références

Science. 2007 Mar 30;315(5820):1860-2
pubmed: 17395832
Annu Rev Psychol. 2015 Jan 3;66:115-42
pubmed: 25251486
Nature. 2014 Mar 27;507(7493):504-7
pubmed: 24670771
Curr Opin Neurobiol. 1998 Apr;8(2):195-201
pubmed: 9635202
Nat Neurosci. 2000 Nov;3 Suppl:1192-8
pubmed: 11127837
Cortex. 2010 Jun;46(6):794-8
pubmed: 19822316
Curr Opin Neurobiol. 2010 Apr;20(2):156-65
pubmed: 20359884
Neuron. 2015 Jan 21;85(2):390-401
pubmed: 25556836
Nature. 1999 Jun 3;399(6735):470-3
pubmed: 10365959
Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14332-41
pubmed: 25205811
Trends Cogn Sci. 2013 Aug;17(8):391-400
pubmed: 23850263
Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18167-72
pubmed: 20921401
J Vis. 2012 May 25;12(5):9
pubmed: 22637710
Nat Commun. 2018 Jan 26;9(1):394
pubmed: 29374153
J Neurosci. 2015 May 6;35(18):7095-105
pubmed: 25948260
Curr Biol. 2014 May 19;24(10):1133-7
pubmed: 24768055
Cereb Cortex. 2016 Sep;26(9):3772-84
pubmed: 26286916
Neuron. 2019 Jul 3;103(1):147-160.e8
pubmed: 31103359
J Neurosci. 2016 Sep 7;36(36):9351-64
pubmed: 27605611
Nature. 1999 Oct 14;401(6754):699-703
pubmed: 10537108
Nature. 1997 Oct 23;389(6653):845-8
pubmed: 9349815
Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11252-5
pubmed: 21690375
Cereb Cortex. 2007 Oct;17(10):2364-74
pubmed: 17190968
J Neurophysiol. 1990 Apr;63(4):814-31
pubmed: 2341879
Psychol Sci. 2005 Aug;16(8):637-43
pubmed: 16102067
Cereb Cortex. 2012 Dec;22(12):2794-810
pubmed: 22190434
J Neurosci. 2006 Jan 25;26(4):1117-27
pubmed: 16436597
J Neurosci. 1996 Aug 15;16(16):5154-67
pubmed: 8756444
Comput Intell Neurosci. 2011;2011:156869
pubmed: 21253357
Neuroimage. 2008 Jun;41(2):354-62
pubmed: 18394927
Neuroimage. 2010 May 15;51(1):112-22
pubmed: 20114076
Front Syst Neurosci. 2016 Jan 08;9:175
pubmed: 26778976
Neuroimage. 2006 Jan 15;29(2):567-77
pubmed: 16289928
Nature. 1997 Nov 20;390(6657):279-81
pubmed: 9384378
Neurosci Biobehav Rev. 2016 Mar;62:100-8
pubmed: 26802451
Cereb Cortex. 2007 Dec;17(12):2914-32
pubmed: 17389630
Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):15008-13
pubmed: 9844006
Cognition. 2010 Oct;117(1):69-79
pubmed: 20659731
Front Hum Neurosci. 2010 Nov 04;4:186
pubmed: 21119777
Cereb Cortex. 1995 Sep-Oct;5(5):470-81
pubmed: 8547793
Exp Brain Res. 1984;55(1):187-91
pubmed: 6745350
Neuroimage. 2013 Jan 1;64:120-33
pubmed: 23006806
Nat Rev Neurosci. 2002 Jul;3(7):553-62
pubmed: 12094211
Science. 1971 Aug 13;173(3997):652-4
pubmed: 4998337
J Neurophysiol. 1989 Feb;61(2):331-49
pubmed: 2918358
Nature. 2013 May 30;497(7451):585-90
pubmed: 23685452
Cognition. 2005 Jul;96(3):B79-88
pubmed: 15996557
J Neurophysiol. 2001 Aug;86(2):912-21
pubmed: 11495960
J Neurophysiol. 2007 May;97(5):3494-507
pubmed: 17360822
Cell Rep. 2018 Feb 20;22(8):2039-2052
pubmed: 29466732
Neuron. 2016 Apr 6;90(1):152-164
pubmed: 26996084
J Neurophysiol. 2009 Oct;102(4):2435-40
pubmed: 19692506
Annu Rev Neurosci. 2003;26:331-54
pubmed: 12626696
Neuron. 2015 Oct 7;88(1):220-35
pubmed: 26447583
Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):883-90
pubmed: 9448255
Nat Commun. 2016 Feb 01;7:10402
pubmed: 26832423

Auteurs

Scott L Brincat (SL)

The Picower Institute for Learning and Memory and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139 USA.

Jacob A Donoghue (JA)

The Picower Institute for Learning and Memory and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139 USA.

Meredith K Mahnke (MK)

The Picower Institute for Learning and Memory and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139 USA.

Simon Kornblith (S)

The Picower Institute for Learning and Memory and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139 USA.

Mikael Lundqvist (M)

The Picower Institute for Learning and Memory and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139 USA; Department of Psychology, Stockholm University, 106 91 Stockholm, Sweden.

Earl K Miller (EK)

The Picower Institute for Learning and Memory and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139 USA. Electronic address: ekmiller@mit.edu.

Articles similaires

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Meal Timing and Anthropometric and Metabolic Outcomes: A Systematic Review and Meta-Analysis.

Hiu Yee Liu, Ashley A Eso, Nathan Cook et al.
1.00
Humans Meals Time Factors Female Adult

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Interhemispheric transfer of working memories.
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Dominance cérébrale › Latéralité fonctionnelle › Interhemispheric transfer of working memories.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Cercopithecidae › Cercopithecinae › Macaca › Macaca mulatta › Interhemispheric transfer of working memories.
questionsmedicales.fr › Phénomènes psychologiques › Processus mentaux › Mémoire › Mémoire à court terme › Interhemispheric transfer of working memories.
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Télencéphale › Cerveau › Cortex cérébral › Lobe frontal › Cortex préfrontal › Interhemispheric transfer of working memories.
questionsmedicales.fr › Phénomènes psychologiques › Processus mentaux › Perception › Perception visuelle › Interhemispheric transfer of working memories.