Multiscale three-dimensional imaging of intact human organs down to the cellular scale using hierarchical phase-contrast tomography.
Journal
bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187
Informations de publication
Date de publication:
03 Feb 2021
03 Feb 2021
Historique:
entrez:
10
2
2021
pubmed:
11
2
2021
medline:
11
2
2021
Statut:
epublish
Résumé
Human organs are complex, three-dimensional and multiscale systems. Spatially mapping the human body down through its hierarchy, from entire organs to their individual functional units and specialised cells, is a major obstacle to fully understanding health and disease. To meet this challenge, we developed hierarchical phase-contrast tomography (HiP-CT), an X-ray phase propagation technique utilising the European Synchrotron Radiation Facility's Extremely Brilliant Source: the world's first high-energy 4
Identifiants
pubmed: 33564772
doi: 10.1101/2021.02.03.429481
pmc: PMC7872374
pii:
doi:
Types de publication
Preprint
Langues
eng
Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : NHLBI NIH HHS
ID : F32 HL134229
Pays : United States
Organisme : Medical Research Council
ID : MR/S007687/1
Pays : United Kingdom
Organisme : NHLBI NIH HHS
ID : R01 HL094567
Pays : United States
Commentaires et corrections
Type : UpdateIn
Références
Kidney Int. 2006 Jul;70(1):104-10
pubmed: 16723986
Lancet Infect Dis. 2020 Apr;20(4):425-434
pubmed: 32105637
Nat Methods. 2012 Jun 28;9(7):676-82
pubmed: 22743772
PLoS One. 2020 Feb 21;15(2):e0229140
pubmed: 32084197
J Microsc. 2002 Apr;206(Pt 1):33-40
pubmed: 12000561
Nat Methods. 2020 Jun;17(6):609-613
pubmed: 32424271
J Anat. 2015 May;226(5):440-6
pubmed: 25846130
Sci Data. 2019 Oct 30;6(1):244
pubmed: 31666530
J Am Soc Nephrol. 2017 Jan;28(1):313-320
pubmed: 27401688
N Engl J Med. 2020 Aug 6;383(6):590-592
pubmed: 32402155
Nat Protoc. 2013 Sep;8(9):1708-17
pubmed: 23928503
Elife. 2017 Dec 05;6:
pubmed: 29206104
JAMA. 2020 Aug 25;324(8):782-793
pubmed: 32648899
Nat Biotechnol. 2020 Mar;38(3):288-292
pubmed: 32024987
Kidney Int. 2016 Feb;89(2):498-505
pubmed: 26535998
Elife. 2020 Aug 20;9:
pubmed: 32815517
Clin Exp Nephrol. 2019 May;23(5):629-637
pubmed: 30635748
J Am Soc Nephrol. 2005 Sep;16(9):2557-64
pubmed: 16049069
J Anat. 2007 May;210(5):578-82
pubmed: 17419811
J Am Soc Nephrol. 2005 Oct;16(10):3102-9
pubmed: 16107583
N Engl J Med. 2020 Jul 9;383(2):120-128
pubmed: 32437596
Curr Opin Nephrol Hypertens. 2008 May;17(3):258-65
pubmed: 18408476
Nature. 2019 Oct;574(7777):187-192
pubmed: 31597973
Am J Physiol Renal Physiol. 2014 Jun 1;306(11):F1381-90
pubmed: 24647716
PLoS Comput Biol. 2016 Nov 21;12(11):e1005217
pubmed: 27870847
J Exp Med. 2021 Mar 1;218(3):
pubmed: 33433624
Nat Methods. 2020 Aug;17(8):793-798
pubmed: 32719530
Lancet Respir Med. 2020 Dec;8(12):1201-1208
pubmed: 32861276
J Am Soc Nephrol. 2003 Oct;14(10):2662-8
pubmed: 14514746
Cell. 2020 Feb 20;180(4):796-812.e19
pubmed: 32059778
Nat Biomed Eng. 2018 Oct;2(10):773-787
pubmed: 31015649
Bioinformatics. 2016 Nov 15;32(22):3532-3534
pubmed: 27412086
Rambam Maimonides Med J. 2011 Oct 31;2(4):e0061
pubmed: 23908819
Nat Neurosci. 2019 Feb;22(2):317-327
pubmed: 30598527
Kidney Int. 2010 Oct;78(7):686-92
pubmed: 20463656
Adv Chronic Kidney Dis. 2016 Jan;23(1):19-28
pubmed: 26709059
Bone. 1993 Mar-Apr;14(2):173-82
pubmed: 8334036
Cancer Res. 2017 Nov 1;77(21):e104-e107
pubmed: 29092951
Cell. 2017 Mar 23;169(1):161-173.e12
pubmed: 28340341
Nature. 2017 Dec 21;552(7685):395-399
pubmed: 29211712
BMC Biol. 2017 Dec 21;15(1):122
pubmed: 29268736
Nat Commun. 2018 Mar 13;9(1):923
pubmed: 29535376
Elife. 2019 Dec 06;8:
pubmed: 31808745
Science. 2011 Sep 9;333(6048):1402-7
pubmed: 21903804
Med Phys. 2019 Dec;46(12):5478-5487
pubmed: 31574166
J Am Soc Nephrol. 2018 Jul;29(7):1960-1969
pubmed: 29789431
Science. 2021 Jan 29;371(6528):
pubmed: 33509999
IEEE Trans Image Process. 2004 Apr;13(4):600-12
pubmed: 15376593
Nat Med. 1996 Apr;2(4):473-5
pubmed: 8597962
Nat Commun. 2020 Apr 27;11(1):1982
pubmed: 32341345
Bioconjug Chem. 2021 Jan 20;32(1):25-42
pubmed: 33325685