Depression and Nigral Neuron Density in Lewy Body Spectrum Diseases.


Journal

Annals of neurology
ISSN: 1531-8249
Titre abrégé: Ann Neurol
Pays: United States
ID NLM: 7707449

Informations de publication

Date de publication:
05 2021
Historique:
revised: 26 01 2021
received: 16 09 2020
accepted: 07 02 2021
pubmed: 11 2 2021
medline: 27 5 2021
entrez: 10 2 2021
Statut: ppublish

Résumé

Parkinson's disease and other Lewy body spectrum diseases (LBDs) are associated with a specific risk for clinical depression. In the present clinicopathological study with 73 patients with LBD, we observed that the substantia nigra pars compacta dopamine neuron density was markedly lower in patients who had comorbid depression antemortem than in nondepressed patients (1.52 vs 2.32 n/mm

Identifiants

pubmed: 33565131
doi: 10.1002/ana.26046
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1046-1050

Informations de copyright

© 2021 The Authors. Annals of Neurology published by Wiley Periodicals LLC on behalf of American Neurological Association.

Références

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Auteurs

Laura Saari (L)

Clinical Neurosciences, University of Turku, Turku, Finland.
Neurocenter, Turku University Hospital, Turku, Finland.

Lauri Heiskanen (L)

Clinical Neurosciences, University of Turku, Turku, Finland.
Neurocenter, Turku University Hospital, Turku, Finland.

Maria Gardberg (M)

Department of Pathology, Laboratory Division, Turku University Hospital and Institute of Biomedicine, University of Turku, Turku, Finland.

Valtteri Kaasinen (V)

Clinical Neurosciences, University of Turku, Turku, Finland.
Neurocenter, Turku University Hospital, Turku, Finland.

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