Meropenem at recommended dose is a potential risk for seizure in hemodialysis patient.


Journal

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
ISSN: 1319-2442
Titre abrégé: Saudi J Kidney Dis Transpl
Pays: Saudi Arabia
ID NLM: 9436968

Informations de publication

Date de publication:
Historique:
entrez: 10 2 2021
pubmed: 11 2 2021
medline: 28 10 2021
Statut: ppublish

Résumé

Dosage adjustment of meropenem is usually recommended in hemodialysis (HD) patients and about 30% of meropenem is cleared during regular HD sessions. However, most of the published trials excluded patients on regular HD. Little is known about the accurate dosage of meropenem needed to avoid central nervous system toxicity. Herein, we report a 65-year-old Saudi female, a known case of end-stage renal disease on regular HD, who was admitted because of pyelonephritis and started on meropenem in the recommended dose according to cultures and sensitivity. She developed tonic-clonic convulsions after the 7

Identifiants

pubmed: 33565459
pii: SaudiJKidneyDisTranspl_2020_31_6_1427_308364
doi: 10.4103/1319-2442.308364
doi:

Substances chimiques

Anti-Bacterial Agents 0
Meropenem FV9J3JU8B1

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1427-1431

Auteurs

Abdullah Al-Hwiesh (A)

Department of Internal Medicine, Division of Nephrology, King Fahd Hospital of the University, Alkhobar; Department of Internal Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Amani Alhwiesh (A)

Department of Internal Medicine, Division of Nephrology, King Fahd Hospital of the University, Alkhobar; Department of Internal Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Ibrahiem Saeed Abdul-Rahman (IS)

Department of Internal Medicine, Division of Nephrology, King Fahd Hospital of the University, Alkhobar; Department of Internal Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Ali Al-Harbi (A)

Diaverum Al-Majdoi Dialysis Center, Eastern Province, Saudi Arabia.

Dujanah Mousa (D)

Diaverum Al-Majdoi Dialysis Center, Eastern Province, Saudi Arabia.

Sami Skiker (S)

Diaverum Al-Majdoi Dialysis Center, Eastern Province, Saudi Arabia.

Abdulaser Abdulkhani (A)

Diaverum Al-Majdoi Dialysis Center, Eastern Province, Saudi Arabia.

Hesham Beheri (H)

Diaverum Al-Majdoi Dialysis Center, Eastern Province, Saudi Arabia.

Morwa Radi (M)

Diaverum Al-Majdoi Dialysis Center, Eastern Province, Saudi Arabia.

Dalal AlKhaldi (D)

Diaverum Al-Majdoi Dialysis Center, Eastern Province, Saudi Arabia.

Azeeza Aldwaihi (A)

Department of Internal Medicine, Division of Nephrology, King Fahd Hospital of the University, Alkhobar; Department of Internal Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Saad Alqahtani (S)

Department of Internal Medicine, Division of Nephrology, King Fahd Hospital of the University, Alkhobar; Department of Internal Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

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Classifications MeSH