Hyperhomocysteinemia and Cardiovascular Disease: Is the Adenosinergic System the Missing Link?
adenosine
adenosine A2A receptors
cardiovascular disease
hydrogen sulfide
hyperhomocysteinemia
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
08 Feb 2021
08 Feb 2021
Historique:
received:
14
01
2021
revised:
30
01
2021
accepted:
04
02
2021
entrez:
11
2
2021
pubmed:
12
2
2021
medline:
13
4
2021
Statut:
epublish
Résumé
The influence of hyperhomocysteinemia (HHCy) on cardiovascular disease (CVD) remains unclear. HHCy is associated with inflammation and atherosclerosis, and it is an independent risk factor for CVD, stroke and myocardial infarction. However, homocysteine (HCy)-lowering therapy does not affect the inflammatory state of CVD patients, and it has little influence on cardiovascular risk. The HCy degradation product hydrogen sulfide (H
Identifiants
pubmed: 33567540
pii: ijms22041690
doi: 10.3390/ijms22041690
pmc: PMC7914561
pii:
doi:
Substances chimiques
Receptor, Adenosine A2A
0
Homocysteine
0LVT1QZ0BA
Hydrogen Sulfide
YY9FVM7NSN
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : ARCHANTEC
ID : None
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