Perinatal Outcomes of Small for Gestational Age in Twin Pregnancies: Twin vs. Singleton Charts.

birth weight chorionicity-specific estimated fetal weight fetal growth restriction reference charts singleton small for gestational age twin pregnancy ultrasound

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
08 Feb 2021
Historique:
received: 01 01 2021
revised: 31 01 2021
accepted: 05 02 2021
entrez: 11 2 2021
pubmed: 12 2 2021
medline: 12 2 2021
Statut: epublish

Résumé

Twin pregnancies are commonly assessed using singleton growth and birth weight reference charts. This practice has led to a significant number of twins labelled as small for gestational age (SGA), causing unnecessary interventions and increased risk of iatrogenic preterm birth. However, the use of twin-specific charts remains controversial. This study aims to assess whether twin-specific estimated fetal weight (EFW) and birth weight (BW) charts are more predictive of adverse outcomes compared to singleton charts. Centiles of EFW and BW were calculated using previously published singleton and twin charts. Categorical data were compared using Chi-square or McNemar tests. The study included 1740 twin pregnancies, with the following perinatal adverse outcomes recorded: perinatal death, preterm birth <34 weeks, hypertensive disorders of pregnancy (HDP) and admissions to the neonatal unit (NNU). Twin-specific charts identified prenatally and postnatally a smaller proportion of infants as SGA compared to singleton charts. However, twin charts showed a higher percentage of adverse neonatal outcomes in SGA infants than singleton charts. For example, perinatal death (SGA 7.2% vs. appropriate for gestational age (AGA) 2%,

Identifiants

pubmed: 33567545
pii: jcm10040643
doi: 10.3390/jcm10040643
pmc: PMC7916041
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Veronica Giorgione (V)

Twins Trust Centre for Research and Clinical Excellence, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0RE, UK.
Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, Cranmer Terrace, London SW17 0RE, UK.
Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0RE, UK.

Corey Briffa (C)

Twins Trust Centre for Research and Clinical Excellence, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0RE, UK.
Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, Cranmer Terrace, London SW17 0RE, UK.

Carolina Di Fabrizio (C)

Twins Trust Centre for Research and Clinical Excellence, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0RE, UK.
Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, Cranmer Terrace, London SW17 0RE, UK.
Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0RE, UK.

Rohan Bhate (R)

Twins Trust Centre for Research and Clinical Excellence, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0RE, UK.
Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0RE, UK.

Asma Khalil (A)

Twins Trust Centre for Research and Clinical Excellence, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0RE, UK.
Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, Cranmer Terrace, London SW17 0RE, UK.
Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0RE, UK.

Classifications MeSH