Total Synthesis and Biological Evaluation of the Potent HIV Latency-Reversing Agent Ansellone A and its Analogues.

Cyclization HIV Infections / drug therapy HIV-1 / chemistry Molecular Structure Sesterterpenes / chemical synthesis

Journal

Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393

Informations de publication

Date de publication:
05 03 2021
Historique:
pubmed: 12 2 2021
medline: 5 10 2021
entrez: 11 2 2021
Statut: ppublish

Résumé

The total synthesis and biological evaluation of the marine sesterterpenoid ansellone A (

Identifiants

DOI: 10.1021/acs.orglett.1c00151 PMID: 33570413
pubmed: 33570413
doi: 10.1021/acs.orglett.1c00151
doi:

Substances chimiques

Sesterterpenes 0
ansellone A 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1720-1725

Auteurs

Mizushi Yanagihara (M)

Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka 565-0871, Japan.

Kenichi Murai (K)

Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka 565-0871, Japan.
ORCID: 0000-0002-1689-6492

Naoki Kishimoto (N)

Department of Environmental and Molecular Health Sciences, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973, Japan.

Towa Abe (T)

Department of Environmental and Molecular Health Sciences, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973, Japan.

Shogo Misumi (S)

Department of Environmental and Molecular Health Sciences, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973, Japan.

Mitsuhiro Arisawa (M)

Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka 565-0871, Japan.
ORCID: 0000-0002-7937-670X

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Classifications MeSH

questionsmedicales.fr › Métabolisme › Cyclisation › Total Synthesis and Biological Evaluation of...
questionsmedicales.fr › Maladies du système immunitaire › Déficits immunitaires › Infections à VIH › Total Synthesis and Biological Evaluation of...
questionsmedicales.fr › Virus › Virus à ARN › Retroviridae › Lentivirus › Lentivirus des primates › VIH (Virus de l'Immunodéficience Humaine) › VIH-1 (Virus de l'Immunodéficience Humaine de type 1) › Total Synthesis and Biological Evaluation of...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Total Synthesis and Biological Evaluation of...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Sesterterpènes › Total Synthesis and Biological Evaluation of...