A Code of Ethics for Gene Drive Research.


Journal

The CRISPR journal
ISSN: 2573-1602
Titre abrégé: CRISPR J
Pays: United States
ID NLM: 101738191

Informations de publication

Date de publication:
02 2021
Historique:
pubmed: 12 2 2021
medline: 25 11 2021
entrez: 11 2 2021
Statut: ppublish

Résumé

Gene drives hold promise for use in controlling insect vectors of diseases, agricultural pests, and for conservation of ecosystems against invasive species. At the same time, this technology comes with potential risks that include unknown downstream effects on entire ecosystems as well as the accidental or nefarious spread of organisms that carry the gene drive machinery. A code of ethics can be a useful tool for all parties involved in the development and regulation of gene drives and can be used to help ensure that a balanced analysis of risks, benefits, and values is taken into consideration in the interest of society and humanity. We have developed a code of ethics for gene drive research with the hope that this code will encourage the development of an international framework that includes ethical guidance of gene drive research and is incorporated into scientific practice by gaining broad agreement and adherence.

Identifiants

pubmed: 33571044
doi: 10.1089/crispr.2020.0096
pmc: PMC7898401
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

19-24

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Auteurs

George J Annas (GJ)

Center for Health Law, Ethics & Human Rights, Boston University School of Public Health, Boston, Massachusetts, USA.

Chase L Beisel (CL)

Helmholtz Institute of RNA-based Infection Research (HIRI), Helmholtz-Centre for Infection Research (HZI), Würzburg, Germany.
Faculty of Medicine, University of Würzburg, Würzburg, Germany.

Kendell Clement (K)

Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Center for Cancer Research and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.

Andrea Crisanti (A)

Department of Life Sciences, Imperial College London, London, United Kingdom.
Department of Molecular Medicine, University of Padova, Padova, Italy.

Stacy Francis (S)

Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Center for Cancer Research and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.

Marco Galardini (M)

Department of Biomedical Engineering and Biological Design Center, Boston University, Boston, Massachusetts, USA.

Roberto Galizi (R)

Centre for Applied Entomology and Parasitology, School of Life Sciences, Keele University, Keele, United Kingdom.

Julian Grünewald (J)

Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Center for Cancer Research and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.

Greta Immobile (G)

Polo d'Innovazione Genomica Genetica e Biologia SCaRL, Siena, Italy.

Ahmad S Khalil (AS)

Department of Biomedical Engineering and Biological Design Center, Boston University, Boston, Massachusetts, USA.
Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts, USA.

Ruth Müller (R)

Polo d'Innovazione Genomica Genetica e Biologia SCaRL, Siena, Italy.
Unit Entomology, Institute of Tropical Medicine, Antwerp, Belgium.

Vikram Pattanayak (V)

Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.

Karl Petri (K)

Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Center for Cancer Research and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.

Ligi Paul (L)

Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Center for Cancer Research and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.

Luca Pinello (L)

Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Center for Cancer Research and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.
Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

Alekos Simoni (A)

Polo d'Innovazione Genomica Genetica e Biologia SCaRL, Siena, Italy.

Chrysanthi Taxiarchi (C)

Department of Life Sciences, Imperial College London, London, United Kingdom.

J Keith Joung (JK)

Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Center for Cancer Research and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.

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