Interneuronal mechanisms for learning-induced switch in a sensory response that anticipates changes in behavioral outcomes.

Lymnaea aversive conditioning central pattern generator electrophysiology inhibitory interneuron invertebrate learning memory neural circuit sensitization

Journal

Current biology : CB
ISSN: 1879-0445
Titre abrégé: Curr Biol
Pays: England
ID NLM: 9107782

Informations de publication

Date de publication:
26 04 2021
Historique:
received: 14 07 2020
revised: 31 10 2020
accepted: 20 01 2021
pubmed: 12 2 2021
medline: 31 12 2021
entrez: 11 2 2021
Statut: ppublish

Résumé

Sensory cues in the natural environment predict reward or punishment, important for survival. For example, the ability to detect attractive tastes indicating palatable food is essential for foraging while the recognition of inedible substrates prevents harm. While some of these sensory responses are innate, they can undergo fundamental changes due to prior experience associated with the stimulus. However, the mechanisms underlying such behavioral switching of an innate sensory response at the neuron and network levels require further investigation. We used the model learning system of Lymnaea stagnalis

Identifiants

pubmed: 33571436
pii: S0960-9822(21)00137-8
doi: 10.1016/j.cub.2021.01.072
pmc: PMC8082272
pii:
doi:

Substances chimiques

Sucrose 57-50-1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1754-1761.e3

Subventions

Organisme : Biotechnology and Biological Sciences Research Council
ID : BBSRC/BB/H009906/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BBSRC/BB/P00766X/1
Pays : United Kingdom

Informations de copyright

Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

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Auteurs

Zsolt Pirger (Z)

Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.

Zita László (Z)

Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.

Souvik Naskar (S)

Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.

Michael Crossley (M)

Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.

Michael O'Shea (M)

Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.

Paul R Benjamin (PR)

Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.

György Kemenes (G)

Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.

Ildikó Kemenes (I)

Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK. Electronic address: i.kemenes@sussex.ac.uk.

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Classifications MeSH