Emerging Natural-Product-Based Treatments for the Management of Osteoarthritis.
bone
cartilage
natural products
osteoarthritis
Journal
Antioxidants (Basel, Switzerland)
ISSN: 2076-3921
Titre abrégé: Antioxidants (Basel)
Pays: Switzerland
ID NLM: 101668981
Informations de publication
Date de publication:
09 Feb 2021
09 Feb 2021
Historique:
received:
13
01
2021
revised:
01
02
2021
accepted:
04
02
2021
entrez:
12
2
2021
pubmed:
13
2
2021
medline:
13
2
2021
Statut:
epublish
Résumé
Osteoarthritis (OA) is a complex degenerative disease in which joint homeostasis is disrupted, leading to synovial inflammation, cartilage degradation, subchondral bone remodeling, and resulting in pain and joint disability. Yet, the development of new treatment strategies to restore the equilibrium of the osteoarthritic joint remains a challenge. Numerous studies have revealed that dietary components and/or natural products have anti-inflammatory, antioxidant, anti-bone-resorption, and anabolic potential and have received much attention toward the development of new therapeutic strategies for OA treatment. In the present review, we provide an overview of current and emerging natural-product-based research treatments for OA management by drawing attention to experimental, pre-clinical, and clinical models. Herein, we review current and emerging natural-product-based research treatments for OA management.
Identifiants
pubmed: 33572126
pii: antiox10020265
doi: 10.3390/antiox10020265
pmc: PMC7914872
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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