Photophysical Properties of Protoporphyrin IX, Pyropheophorbide-a and Photofrin

Photofrin® absorption fluorescence photodynamic therapy protoporphyrin IX pyropheophorbide-a singlet oxygen

Journal

Pharmaceuticals (Basel, Switzerland)
ISSN: 1424-8247
Titre abrégé: Pharmaceuticals (Basel)
Pays: Switzerland
ID NLM: 101238453

Informations de publication

Date de publication:
09 Feb 2021
Historique:
received: 26 01 2021
accepted: 07 02 2021
entrez: 12 2 2021
pubmed: 13 2 2021
medline: 13 2 2021
Statut: epublish

Résumé

Photodynamic therapy (PDT) is an innovative treatment of malignant or diseased tissues. The effectiveness of PDT depends on light dosimetry, oxygen availability, and properties of the photosensitizer (PS). Depending on the medium, photophysical properties of the PS can change leading to increase or decrease in fluorescence emission and formation of reactive oxygen species (ROS) especially singlet oxygen (

Identifiants

pubmed: 33572282
pii: ph14020138
doi: 10.3390/ph14020138
pmc: PMC7914864
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Bauyrzhan Myrzakhmetov (B)

LRGP UMR 7274, CNRS, University of Lorraine, 54000 Nancy, France.
Department of Chemistry and Chemical Technology, M.Kh. Dulaty Taraz Regional University, Taraz 080012, Kazakhstan.

Philippe Arnoux (P)

LRGP UMR 7274, CNRS, University of Lorraine, 54000 Nancy, France.

Serge Mordon (S)

ONCO-THAI U1189, INSERM, CHU Lille, University of Lille, 59000 Lille, France.

Samir Acherar (S)

LCPM UMR 7375, CNRS, University of Lorraine, 54000 Nancy, France.

Irina Tsoy (I)

Department of Chemistry and Chemical Technology, M.Kh. Dulaty Taraz Regional University, Taraz 080012, Kazakhstan.

Céline Frochot (C)

LRGP UMR 7274, CNRS, University of Lorraine, 54000 Nancy, France.

Classifications MeSH