Immunohistochemical Biomarkers as a Surrogate of Molecular Analysis in Ovarian Carcinomas: A Review of the Literature.
biomarkers
immunohistochemistry
molecular classification
ovarian cancer
Journal
Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402
Informations de publication
Date de publication:
29 Jan 2021
29 Jan 2021
Historique:
received:
31
12
2020
revised:
26
01
2021
accepted:
27
01
2021
entrez:
12
2
2021
pubmed:
13
2
2021
medline:
13
2
2021
Statut:
epublish
Résumé
The term "ovarian carcinoma" encompasses at least five different malignant neoplasms: high-grade serous carcinoma, low-grade serous carcinoma, endometrioid carcinoma, mucinous carcinoma, and clear cell carcinoma. These five histotypes demonstrated distinctive histological, molecular, and clinical features. The rise of novel target therapies and of a tailored oncological approach has demanded an integrated multidisciplinary approach in the setting of ovarian carcinoma. The need to implement a molecular-based classification in the worldwide diagnostic and therapeutic setting of ovarian cancer demanded a search for easy-to-use and cost-effective molecular-surrogate biomarkers, relying particularly on immunohistochemical analysis. The present review focuses on the role of immunohistochemistry as a surrogate of molecular analysis in the everyday diagnostic approach to ovarian carcinomas.
Identifiants
pubmed: 33572888
pii: diagnostics11020199
doi: 10.3390/diagnostics11020199
pmc: PMC7911119
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Am J Surg Pathol. 2020 Aug;44(8):1050-1060
pubmed: 32384321
Am J Pathol. 2016 Apr;186(4):733-47
pubmed: 27012190
Hum Pathol. 2018 Feb;72:100-106
pubmed: 29133142
Ann Oncol. 2019 Aug 1;30(8):1232-1243
pubmed: 31056702
BMC Cancer. 2009 Dec 10;9:433
pubmed: 20003286
Oncotarget. 2016 Mar 22;7(12):13587-98
pubmed: 26871470
J Clin Pathol. 2020 Apr;73(4):191-196
pubmed: 31719105
Ann Oncol. 2018 May 1;29(5):1203-1210
pubmed: 29635390
Lancet Oncol. 2013 Aug;14(9):853-62
pubmed: 23845225
Am J Surg Pathol. 2011 Jan;35(1):36-44
pubmed: 21164285
Best Pract Res Clin Obstet Gynaecol. 2017 May;41:15-30
pubmed: 28277307
Invest New Drugs. 2015 Dec;33(6):1267-70
pubmed: 26490654
Am J Surg Pathol. 2008 Feb;32(2):269-74
pubmed: 18223330
Lancet. 2017 Oct 28;390(10106):1949-1961
pubmed: 28916367
Gynecol Oncol. 2014 Jul;134(1):15-9
pubmed: 24844595
Int J Gynecol Cancer. 2016 Jun;26(5):933-8
pubmed: 26937754
Am J Surg Pathol. 2017 May;41(5):685-695
pubmed: 28125452
Gynecol Oncol. 2015 May;137(2):343-50
pubmed: 25725131
Histopathology. 2020 Jan;76(1):157-170
pubmed: 31846530
Cancer Cell. 2017 Mar 13;31(3):411-423
pubmed: 28292439
BMC Cancer. 2018 Mar 27;18(1):347
pubmed: 29587661
Cancer Res. 2004 Nov 1;64(21):7678-81
pubmed: 15520168
Am J Surg Pathol. 2007 Feb;31(2):161-9
pubmed: 17255760
N Z Med J. 2013 Sep 13;126(1382):70-7
pubmed: 24154771
Nature. 2011 Jun 29;474(7353):609-15
pubmed: 21720365
Gynecol Oncol. 2012 Apr;125(1):271-7
pubmed: 22155675
J Clin Oncol. 2010 Aug 1;28(22):3570-6
pubmed: 20606085
Cancer Treat Rev. 2016 Jul;48:61-8
pubmed: 27362548
Nat Commun. 2014 Sep 19;5:5006
pubmed: 25233892
N Engl J Med. 2016 Dec;375(22):2154-2164
pubmed: 27717299
CA Cancer J Clin. 2018 Jan;68(1):7-30
pubmed: 29313949
Int J Gynecol Pathol. 2012 May;31(3):243-53
pubmed: 22498942
Int J Gynecol Pathol. 2020 Jan;39(1):84-92
pubmed: 30575604
Lancet Oncol. 2011 Oct;12(11):1071-80
pubmed: 21616717
Mod Pathol. 2011 Oct;24(10):1368-79
pubmed: 21572397
Gynecol Oncol. 2016 May;141(2):293-302
pubmed: 26972336
Hum Mutat. 2017 Feb;38(2):226-235
pubmed: 27767231
Anticancer Res. 2017 Nov;37(11):5955-5965
pubmed: 29061774
Clin Cancer Res. 2020 Oct 15;26(20):5400-5410
pubmed: 32737030
Clin Med Res. 2007 Mar;5(1):35-44
pubmed: 17456833
J Pathol Clin Res. 2016 Jul 13;2(4):247-258
pubmed: 27840695
Am J Surg Pathol. 2010 Mar;34(3):433-43
pubmed: 20154587
Histopathology. 2019 Feb;74(3):452-462
pubmed: 30326146
Int J Gynecol Cancer. 2015 Sep;25(7):1187-93
pubmed: 26166557
Am J Surg Pathol. 2018 Feb;42(2):227-233
pubmed: 28984674
Cell Rep. 2014 Jan 30;6(2):377-87
pubmed: 24440717
Adv Anat Pathol. 2013 Nov;20(6):378-86
pubmed: 24113308
Curr Oncol Rep. 2011 Dec;13(6):442-9
pubmed: 21913063
Mod Pathol. 2021 Feb;34(2):490-501
pubmed: 32801341
Histopathology. 2020 Jan;76(1):37-51
pubmed: 31846521
N Engl J Med. 2012 Apr 12;366(15):1382-92
pubmed: 22452356
Am J Surg Pathol. 1987 Sep;11(9):661-7
pubmed: 2443026
Am J Surg Pathol. 2015 Jul;39(7):983-92
pubmed: 25723110
JAMA Oncol. 2015 Dec;1(9):1319-23
pubmed: 26181000
Int J Mol Sci. 2017 Feb 27;18(3):
pubmed: 28264438
Am J Surg Pathol. 2000 Nov;24(11):1447-64
pubmed: 11075847
Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18538-43
pubmed: 16344461
J Natl Cancer Inst. 2019 Jan 1;111(1):60-68
pubmed: 29718305
Int J Mol Sci. 2019 Jun 15;20(12):
pubmed: 31208030
Histopathology. 2018 Jan;72(2):248-258
pubmed: 28795426
J Clin Oncol. 2019 Feb 1;37(4):286-295
pubmed: 30376427
Am J Surg Pathol. 2020 Mar;44(3):316-328
pubmed: 31876585
Am J Surg Pathol. 2021 Jan;45(1):68-76
pubmed: 32769429
Oncology (Williston Park). 2016 Feb;30(2):166-76
pubmed: 26892153
Semin Diagn Pathol. 2005 Feb;22(1):3-32
pubmed: 16512597
Obstet Gynecol. 2009 Apr;113(4):957-966
pubmed: 19305347
Am J Surg Pathol. 2016 Mar;40(3):419-32
pubmed: 26551622
Onco Targets Ther. 2014 Sep 23;7:1647-52
pubmed: 25285014
Mod Pathol. 2017 Dec;30(12):1748-1759
pubmed: 28776572
J Pathol Clin Res. 2018 Oct;4(4):250-261
pubmed: 30062862
Am J Surg Pathol. 2018 Dec;42(12):1596-1606
pubmed: 30148742
Biomed Res Int. 2014;2014:787143
pubmed: 25136623
Lancet Oncol. 2017 Jan;18(1):75-87
pubmed: 27908594
Dis Markers. 2004;20(4-5):199-206
pubmed: 15528785
Mod Pathol. 2013 Nov;26(11):1525-35
pubmed: 23702729
N Engl J Med. 2018 Dec 27;379(26):2495-2505
pubmed: 30345884
Am J Surg Pathol. 2020 May;44(5):649-656
pubmed: 32294063
J Natl Cancer Inst. 2003 Mar 19;95(6):484-6
pubmed: 12644542
Lancet Oncol. 2011 Jun;12(6):594-603
pubmed: 21163703
Histopathology. 2015 May;66(6):808-15
pubmed: 25065903
Virchows Arch. 2020 Jul;477(1):83-91
pubmed: 31980961
J Pathol. 2014 Mar;232(4):473-81
pubmed: 24338723
Histopathology. 2020 Jan;76(1):76-92
pubmed: 31846535
Am J Surg Pathol. 2007 Jul;31(7):1007-12
pubmed: 17592266
J Pathol. 2013 Dec;231(4):449-56
pubmed: 24549645
Nat Rev Cancer. 2011 Dec 23;12(1):68-78
pubmed: 22193408
J Natl Cancer Inst. 2014 Dec 12;107(1):402
pubmed: 25505230
N Engl J Med. 2019 Mar 28;380(13):1256-1266
pubmed: 30917260
Int J Gynecol Pathol. 2019 Jan;38 Suppl 1:S64-S74
pubmed: 30550484
Nat Commun. 2019 Sep 2;10(1):3935
pubmed: 31477716
Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12238-12243
pubmed: 27791010
Clin Cancer Res. 2014 Sep 15;20(18):4816-26
pubmed: 24963051
Am J Surg Pathol. 2020 Nov;44(11):1573-1579
pubmed: 32804882
Ann Oncol. 2014 Dec;25(12):2372-2378
pubmed: 25281711
Int J Gynecol Cancer. 2014 Nov;24(9 Suppl 3):S55-60
pubmed: 25341582
Oncotarget. 2015 Nov 10;6(35):37663-77
pubmed: 26506417
JCO Precis Oncol. 2018 Nov;2:1-14
pubmed: 35135122
Pathology. 2011 Jan;43(1):84-5; author reply 85-6
pubmed: 21240077
Histopathology. 2018 Sep;73(3):438-443
pubmed: 29770477
Mod Pathol. 2012 Apr;25(4):625-36
pubmed: 22193042
Nature. 2013 May 2;497(7447):67-73
pubmed: 23636398
Clin Cancer Res. 2019 Feb 1;25(3):1087-1097
pubmed: 30413523
Mod Pathol. 2009 Sep;22(9):1133-8
pubmed: 19543244
J Clin Invest. 2013 Jan;123(1):517-25
pubmed: 23257362
N Engl J Med. 2019 Dec 19;381(25):2391-2402
pubmed: 31562799
Mol Cancer Res. 2018 Dec;16(12):1819-1825
pubmed: 30037854
Carcinogenesis. 2008 Apr;29(4):673-80
pubmed: 17942460
Hum Pathol. 2018 Oct;80:11-27
pubmed: 29944973