Six-Month Survival After Extracorporeal Membrane Oxygenation for Severe COVID-19.
ARDS
COVID-19
ECLS
ECMO
acute respiratory distress syndrome
coronavirus disease 2019
extracorporeal membrane oxygenation
Journal
Journal of cardiothoracic and vascular anesthesia
ISSN: 1532-8422
Titre abrégé: J Cardiothorac Vasc Anesth
Pays: United States
ID NLM: 9110208
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
received:
11
12
2020
revised:
12
01
2021
accepted:
15
01
2021
pubmed:
13
2
2021
medline:
3
6
2021
entrez:
12
2
2021
Statut:
ppublish
Résumé
The authors evaluated the outcome of adult patients with coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS) requiring the use of extracorporeal membrane oxygenation (ECMO). Multicenter retrospective, observational study. Ten tertiary referral university and community hospitals. Patients with confirmed severe COVID-19-related ARDS. Venovenous or venoarterial ECMO. One hundred thirty-two patients (mean age 51.1 ± 9.7 years, female 17.4%) were treated with ECMO for confirmed severe COVID-19-related ARDS. Before ECMO, the mean Sequential Organ Failure Assessment score was 10.1 ± 4.4, mean pH was 7.23 ± 0.09, and mean PaO The present findings suggested that about half of adult patients with severe COVID-19-related ARDS can be managed successfully with ECMO with sustained results at six months. Decreased arterial pH before ECMO was associated significantly with early mortality. Therefore, the authors hypothesized that initiation of ECMO therapy before severe metabolic derangements subset may improve survival rates significantly in these patients. These results should be viewed in the light of a strict patient selection policy and may not be replicated in patients with advanced age or multiple comorbidities. identifier, NCT04383678.
Identifiants
pubmed: 33573928
pii: S1053-0770(21)00062-8
doi: 10.1053/j.jvca.2021.01.027
pmc: PMC7816613
pii:
doi:
Banques de données
ClinicalTrials.gov
['NCT04383678']
Types de publication
Journal Article
Multicenter Study
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
1999-2006Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.
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