The Potential Importance of MicroRNAs as Novel Indicators How to Manage Patients with Juvenile Idiopathic Arthritis More Effectively.
Journal
Journal of immunology research
ISSN: 2314-7156
Titre abrégé: J Immunol Res
Pays: Egypt
ID NLM: 101627166
Informations de publication
Date de publication:
2021
2021
Historique:
received:
15
07
2020
revised:
20
12
2020
accepted:
11
01
2021
entrez:
12
2
2021
pubmed:
13
2
2021
medline:
15
10
2021
Statut:
epublish
Résumé
Small, noncoding sequences of ribonucleic acid called microRNAs (miRNAs, miR) are functioning as posttranscriptional regulators of gene expression. As they draw increasing attention of rheumatologists, there is a growing body of evidence concerning specific molecules that may affect the long-term care of patients with inflammatory arthritides. Findings involving children with juvenile idiopathic arthritis (JIA) are still limited though. The aim of the study was to browse the available data on microRNAs which may be utilized as potential biomarkers helpful in diagnosing and monitoring JIA patients. The review contains a brief summary on the most studied sequences: miR-16, miR-125a-5p, miR-146a, miR-155, and miR-223. It is complemented with other miRNAs possibly relevant for JIA (miR-145, miR-23b, miR-27a, and miR-204) and discussion on challenges for using miRNAs in pediatric rheumatology (particularly, issues regarding specificity of biomarkers and measurements involving synovial fluid).
Identifiants
pubmed: 33575364
doi: 10.1155/2021/9473508
pmc: PMC7864733
doi:
Substances chimiques
Biomarkers
0
MicroRNAs
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
9473508Informations de copyright
Copyright © 2021 Krzysztof Orczyk and Elzbieta Smolewska.
Déclaration de conflit d'intérêts
The authors declare no competing interests.
Références
Clin Rheumatol. 2019 Jun;38(6):1753-1765
pubmed: 30707326
Allergy. 2012 Mar;67(3):362-70
pubmed: 22229716
Spine (Phila Pa 1976). 2016 May;41(9):735-42
pubmed: 27128253
Int J Rheum Dis. 2017 Nov;20(11):1631-1637
pubmed: 29105307
Autoimmun Rev. 2019 Aug;18(8):796-804
pubmed: 31176874
Immunity. 2007 Dec;27(6):847-59
pubmed: 18055230
Autoimmun Rev. 2019 Nov;18(11):102391
pubmed: 31520804
Nat Immunol. 2010 Feb;11(2):141-7
pubmed: 19946272
Front Med (Lausanne). 2018 Jul 03;5:186
pubmed: 30018954
Nan Fang Yi Ke Da Xue Xue Bao. 2011 Feb;31(2):320-3
pubmed: 21354921
Med Sci Monit. 2018 Jul 30;24:5292-5300
pubmed: 30059491
J Rheumatol. 2018 Jan;45(1):53-61
pubmed: 29142030
J Rheumatol. 2015 Oct;42(10):1746-1751
pubmed: 26233505
Nucleic Acids Res. 2010 Jun;38(10):3222-32
pubmed: 20144951
Gene. 2019 Dec 15;720:144081
pubmed: 31473322
J Rheumatol. 2019 Feb;46(2):190-197
pubmed: 30275259
Immunol Cell Biol. 2020 Mar;98(3):171-186
pubmed: 31856314
Arthritis Rheum. 2012 Nov;64(11):3809-17
pubmed: 22740338
Nat Cell Biol. 2010 May;12(5):513-9
pubmed: 20418869
Postepy Hig Med Dosw (Online). 2016 Jul 06;70(0):743-50
pubmed: 27383571
Expert Rev Clin Immunol. 2018 Nov;14(11):933-944
pubmed: 30269617
Biosci Rep. 2020 Jan 31;40(1):
pubmed: 31894846
Arthritis Res Ther. 2017 Dec 01;19(1):261
pubmed: 29191214
Biosci Rep. 2019 Jul 18;39(7):
pubmed: 31235484
Curr Opin Rheumatol. 2017 Sep;29(5):523-529
pubmed: 28538013
Mol Immunol. 2016 Sep;77:205-12
pubmed: 27541693
Front Immunol. 2019 Jun 27;10:1475
pubmed: 31316517
Front Immunol. 2019 Sep 13;10:2217
pubmed: 31572403
J Rheumatol. 2016 Aug;43(8):1607-14
pubmed: 27252421
Clin Rheumatol. 2018 Dec;37(12):3255-3262
pubmed: 30171379
J Hematol Oncol. 2013 Jan 15;6:6
pubmed: 23321005
J Immunol. 2012 Oct 15;189(8):4175-81
pubmed: 22984082
Discov Med. 2019 Jul;28(151):47-68
pubmed: 31465725
World J Pediatr. 2020 Feb;16(1):99-110
pubmed: 31102153
Arthritis Rheum. 2012 Oct;64(10):3240-5
pubmed: 22674011
Microrna. 2013;2(1):63-71
pubmed: 25019052
Ann Rheum Dis. 2014 Oct;73(10):1898-904
pubmed: 23897768
Front Immunol. 2019 Jan 11;9:3099
pubmed: 30687316
Arthritis Res Ther. 2008;10(4):R101
pubmed: 18759964
Gene. 2019 Sep 5;712:143911
pubmed: 31176730
Cells. 2019 Nov 26;8(12):
pubmed: 31779271
J Leukoc Biol. 2018 Jan;103(1):71-85
pubmed: 29345059
Exp Ther Med. 2016 Jun;11(6):2531-2536
pubmed: 27284344
PLoS One. 2012;7(1):e30772
pubmed: 22292036
Reumatologia. 2017;55(1):10-14
pubmed: 28386137
Ann Rheum Dis. 2015 Jun;74(6):1265-74
pubmed: 24562503
Biomed Pharmacother. 2019 Apr;112:108583
pubmed: 30780103
Biochimie. 2015 Dec;119:16-26
pubmed: 26453808
J Rheumatol. 2020 Feb;47(2):188-196
pubmed: 31092710
Curr Opin Rheumatol. 2018 Mar;30(2):188-196
pubmed: 29194108
Arthritis Rheum. 2012 Jun;64(6):1771-9
pubmed: 22161761
Sci Rep. 2016 Jun 07;6:27453
pubmed: 27271962
Clin Exp Immunol. 2017 Mar;187(3):327-336
pubmed: 27880973
Clin Immunol. 2007 Dec;125(3):247-56
pubmed: 17870671
Biochem Biophys Res Commun. 2013 Sep 27;439(3):407-12
pubmed: 23988448
Int Immunopharmacol. 2016 Mar;32:46-54
pubmed: 26800097
Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11193-8
pubmed: 21690378
J Immunol Res. 2018 Oct 22;2018:5349837
pubmed: 30426025
Sci Rep. 2016 Jan 29;6:20059
pubmed: 26821827
Mod Rheumatol. 2016;26(2):224-32
pubmed: 26054419
Swiss Med Wkly. 2011 Mar 18;141:w13175
pubmed: 21416408
Cell Res. 2008 Oct;18(10):997-1006
pubmed: 18766170
Arthritis Rheumatol. 2016 Sep;68(9):2300-13
pubmed: 27014994
PLoS One. 2013 Jul 18;8(7):e69118
pubmed: 23874885
Int J Mol Sci. 2017 Aug 31;18(9):
pubmed: 28858208
BMC Musculoskelet Disord. 2010 Sep 15;11:209
pubmed: 20840794
CNS Neurosci Ther. 2012 Sep;18(9):722-8
pubmed: 22709411
J Clin Lab Anal. 2019 Sep;33(7):e22953
pubmed: 31245894
DNA Cell Biol. 2016 Dec;35(12):853-860
pubmed: 27875659
Rheumatol Int. 2014 Oct;34(10):1395-400
pubmed: 24719227
Immunol Med. 2019 Dec;42(4):156-161
pubmed: 31770498
Hum Immunol. 2010 Feb;71(2):206-11
pubmed: 19931339
J Immunol. 2016 Sep 15;197(6):2219-28
pubmed: 27534557
Cytokine Growth Factor Rev. 2018 Feb;39:1-18
pubmed: 29398400
Inflamm Bowel Dis. 2018 Jun 8;24(7):1547-1557
pubmed: 29668922
J Clin Med. 2019 Jan 17;8(1):
pubmed: 30658492
Genome Biol. 2005;6(8):R71
pubmed: 16086853
Clin Rheumatol. 2019 Mar;38(3):877-884
pubmed: 30511295
Lupus. 2015 Mar;24(3):240-7
pubmed: 25253569
Med Sci Monit. 2017 Nov 18;23:5488-5494
pubmed: 29150993
Front Immunol. 2018 Oct 16;9:2381
pubmed: 30459760
Arthritis Res Ther. 2010;12(3):R86
pubmed: 20470394
J Biol Chem. 2011 Jan 21;286(3):1786-94
pubmed: 21097505
PLoS One. 2012;7(8):e42971
pubmed: 22937006
Arthritis Res Ther. 2017 Nov 10;19(1):249
pubmed: 29126434
J Cell Biochem. 2019 Mar 1;:
pubmed: 30825220
Reumatologia. 2016;54(3):95-6
pubmed: 27504017
Clin Exp Immunol. 2014 Sep;177(3):641-51
pubmed: 24816316
J Immunol. 2009 Aug 1;183(3):2150-8
pubmed: 19596990
Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12481-6
pubmed: 16885212
J Biol Chem. 2009 Mar 13;284(11):6605-9
pubmed: 19126550
Arthritis Res Ther. 2017 Dec 22;19(1):288
pubmed: 29273071
Arthritis Rheum. 2008 Apr;58(4):1001-9
pubmed: 18383392
J Immunol Methods. 2013 Dec 31;400-401:106-10
pubmed: 24120842
Mediators Inflamm. 2014;2014:342524
pubmed: 24778468
Arthritis Rheumatol. 2019 Jun;71(6):846-863
pubmed: 31021537
Clin Rheumatol. 2015 Oct;34(10):1705-12
pubmed: 25846830
Int Immunopharmacol. 2018 Oct;63:35-42
pubmed: 30075427