The impact of obesity on seasonal influenza: a single-center, retrospective study conducted in Israel.
BMI
Infection
Influenza
Mortality
Obesity
Journal
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
ISSN: 1435-4373
Titre abrégé: Eur J Clin Microbiol Infect Dis
Pays: Germany
ID NLM: 8804297
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
received:
23
10
2020
accepted:
24
01
2021
pubmed:
13
2
2021
medline:
9
10
2021
entrez:
12
2
2021
Statut:
ppublish
Résumé
Obesity is associated with an increased susceptibility to infections. Several studies have reported adverse clinical outcomes of influenza among obese individuals. Our aim was to examine the association between obesity and the clinical outcomes of hospitalized adult patients ill with seasonal influenza. Consecutive hospitalized adult patients between 10/2017 and 4/2018 with laboratory confirmed influenza A and B were divided into an obese group (body mass index (BMI) ≥ 30 kg/m
Identifiants
pubmed: 33575963
doi: 10.1007/s10096-021-04174-w
pii: 10.1007/s10096-021-04174-w
pmc: PMC7877522
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1471-1476Références
Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C et al (2014) Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 384:766–781. https://doi.org/10.1016/S0140-6736(14)60460-8
doi: 10.1016/S0140-6736(14)60460-8
pubmed: 4624264
pmcid: 4624264
Tsai AG, Wadden TA (2013) In the clinic: obesity. Ann Intern Med 159:ITC3-1–ITC3-15; quiz ITC3-16. https://doi.org/10.7326/0003-4819-159-5-201309030-01003
doi: 10.7326/0003-4819-159-5-201309030-01003
Falagas ME, Kompoti M (2006) Obesity and infection. Lancet Infect Dis 6:438–446. https://doi.org/10.1016/S1473-3099(06)70523-0
doi: 10.1016/S1473-3099(06)70523-0
pubmed: 16790384
Farmakiotis D (2013) Obesity and serious infections. Ann Intern Med 159:859. https://doi.org/10.7326/0003-4819-159-12-201312170-00021
doi: 10.7326/0003-4819-159-12-201312170-00021
pubmed: 24343400
Power K, Davies MM, Hargest R, Phillips S, Torkington J, Morris C (2014) A case–control study of risk factors for wound infection in a colorectal unit. Ann R Coll Surg Engl 96:37–40. https://doi.org/10.1308/003588414X13824511650137
doi: 10.1308/003588414X13824511650137
pubmed: 24417828
pmcid: 5137653
Huttunen R, Syrjänen J (2013) Obesity and the risk and outcome of infection. Int J Obes 37:333–340. https://doi.org/10.1038/ijo.2012.62
doi: 10.1038/ijo.2012.62
Falagas ME, Athanasoulia AP, Peppas G, Karageorgopoulos DE (2009) Effect of body mass index on the outcome of infections: a systematic review. Obes Rev 10:280–289. https://doi.org/10.1111/j.1467-789X.2008.00546.x
doi: 10.1111/j.1467-789X.2008.00546.x
pubmed: 19243518
Atamna A, Elis A, Gilady E, Gitter-Azulay L, Bishara J (2017) How obesity impacts outcomes of infectious diseases. Eur J Clin Microbiol Infect Dis 36:585–591. https://doi.org/10.1007/s10096-016-2835-1
doi: 10.1007/s10096-016-2835-1
pubmed: 27864622
Kwong JC, Campitelli MA, Rosella LC (2011) Obesity and respiratory hospitalizations during influenza seasons in Ontario, Canada: a cohort study. Clin Infect Dis 53:413–421. https://doi.org/10.1093/cid/cir442
doi: 10.1093/cid/cir442
pubmed: 21844024
pmcid: 3156143
Almond MH, Edwards MR, Barclay WS, Johnston SL (2013) Obesity and susceptibility to severe outcomes following respiratory viral infection. Thorax 68:684–686. https://doi.org/10.1136/thoraxjnl-2012-203009
doi: 10.1136/thoraxjnl-2012-203009
pubmed: 23436045
Riquelme R, Jiménez P, Videla AJ, Lopez H, Chalmers J, Singanayagam A et al (2011) Predicting mortality in hospitalized patients with 2009 H1N1 influenza pneumonia. Int J Tuberc Lung Dis 15(4):542–546. https://doi.org/10.5588/ijtld.10.0539
doi: 10.5588/ijtld.10.0539
pubmed: 21396216
Singanayagam A, Singanayagam A, Chalmers JD (2013) Obesity is associated with improved survival in community-acquired pneumonia. Eur Respir J 42:180–187. https://doi.org/10.1183/09031936.00115312
doi: 10.1183/09031936.00115312
pubmed: 23222873
Corrales-Medina VF, Valayam J, Serpa JA, Rueda AM, Musher DM (2011) The obesity paradox in community-acquired bacterial pneumonia. Int J Infect Dis 15:e54–e57. https://doi.org/10.1016/j.ijid.2010.09.011
doi: 10.1016/j.ijid.2010.09.011
pubmed: 21095152
Kahlon S, Eurich DT, Padwal RS, Malhotra A, Minhas-Sandhu JK, Marrie TJ et al (2013) Obesity and outcomes in patients hospitalized with pneumonia. Clin Microbiol Infect 19:709–716. https://doi.org/10.1111/j.1469-0691.2012.04003.x
doi: 10.1111/j.1469-0691.2012.04003.x
pubmed: 22963453
King P, Mortensen EM, Bollinger M, Restrepo MI, Copeland LA, Pugh MJ et al (2013) Impact of obesity on outcomes for patients hospitalised with pneumonia. Eur Respir J 41(4):929–934. https://doi.org/10.1183/09031936.00185211
doi: 10.1183/09031936.00185211
pubmed: 22936705
Centers for Disease Control and Prevention (2010) Estimates of deaths associated with seasonal influenza - United States, 1976-2007. Morb Mortal Wkly Rep 59:1057–1062
Hancock K, Veguilla V, Lu X, Zhong W, Butler EN, Sun H, Liu F, Dong L, DeVos JR, Gargiullo PM, Brammer TL, Cox NJ, Tumpey TM, Katz JM (2009) Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus. NEJM 361:1945–1952. https://doi.org/10.1056/NEJMoa0906453
doi: 10.1056/NEJMoa0906453
pubmed: 19745214
Reichert TA, Simonsen L, Sharma A, Pardo SA, Fedson DS, Miller MA (2004) Influenza and the winter increase in mortality in the United States, 1959-1999. Am J Epidemiol 160:492–502. https://doi.org/10.1093/aje/kwh227
doi: 10.1093/aje/kwh227
pubmed: 15321847
Simonsen L, Clarke MJ, Williamson GD, Stroup DF, Arden NH, Schonberger LB (1997) The impact of influenza epidemics onmortality:introducing a severity index. Am J Public Health 87:1944–1950. https://doi.org/10.2105/ajph.87.12.1944
doi: 10.2105/ajph.87.12.1944
pubmed: 9431281
pmcid: 1381234
Atamna A, Babitch T, Bracha M, Sorek N, Haim BZ, Elis A, Bishara J, Avni T (2019) Statins and outcomes of hospitalized patients with laboratory-confirmed 2017-2018 influenza. Eur J Clin Microbiol Infect Dis 38:2341–2348. https://doi.org/10.1007/s10096-019-03684-y
doi: 10.1007/s10096-019-03684-y
pubmed: 31463620
Morgan OW, Bramley A, Fowlkes A, Freedman DS, Taylor TH, Gargiullo P, Belay B, Jain S, Cox C, Kamimoto, Fiore A, Finelli L, Olsen SJ, Fry (2010) Morbid obesity as a risk factor for hospitalization and death due to 2009 pandemic influenza A(H1N1) disease. PLoS ONE 5:e9694. https://doi.org/10.1371/journal.pone.0009694
doi: 10.1371/journal.pone.0009694
pubmed: 20300571
pmcid: 2837749
Van Kerkhove MD, Vandemaele KA, Shinde V, Jaramillo-Gutierrez G, Koukounari A, Donnelly CA et al (2011) Risk factors for severe outcomes following 2009 influenza A (H1N1) infection: a global pooled analysis. PLoS Med 8:e1001053. https://doi.org/10.1371/journal.pmed.1001053samerefas25
doi: 10.1371/journal.pmed.1001053samerefas25
pubmed: 21750667
pmcid: 3130021
Martin ET, Archer C, McRoberts J, Kulik J, Thurston T, Lephart P, Kaye KS (2013) Epidemiology of severe influenza outcomes among adult patients with obesity in Detroit, Michigan, 2011. Influenza Other Respir Viruses 7:1004–1007. https://doi.org/10.1111/irv.12115
doi: 10.1111/irv.12115
pubmed: 23594280
pmcid: 3749256
Centers for Disease Control and Prevention (CDC) (2009) Intensive-care patients with severe novel influenza A (H1N1) virus infection-Michigan, June 2009. Morb Mortal Wkly Rep 58:749–752
Maier HE, Lopez R, Sanchez N, Ng S, Gresh L, Ojeda S et al (2018) Obesity increases the duration of influenza A virua shedding in adults. J Infect Dis 218:1378–1382. https://doi.org/10.1093/infdis/jiy370
doi: 10.1093/infdis/jiy370
pubmed: 30085119
pmcid: 6151083
Blumentals WA, Nevitt A, Peng MM, Toovey S (2012) Body mass index and the incidence of influenza-associated pneumonia in a UK primary care cohort. Influenza Other Respir Viruses 6:28–36. https://doi.org/10.1111/j.1750-2659.2011.00262.x
doi: 10.1111/j.1750-2659.2011.00262.x
pubmed: 21668664
Zhang ZXZ, Mar Kyaw W, Ho HJ, Tay MZ, Huang H, Aung Hein A, Chow A (2011) Seasonal influenza-associated intensive care unit admission and death in tropical Singapore, 2011-2015. J Clin Virol 117:73–79. https://doi.org/10.1016/j.jcv.2019.06.005
doi: 10.1016/j.jcv.2019.06.005
Avni T, Babich T, Nir A, Yahav D, Shaked H, Sorek N, Zvi HB, Bishara J, Atamna A (2020) Comparison of clinical outcomes of influenza A and B at the 2017-2018 influenza season: a cohort study. Eur J Clin Microbiol Infect Dis 39:1109–1114. https://doi.org/10.1007/s10096-020-03822-x
doi: 10.1007/s10096-020-03822-x
pubmed: 31989376
Reddy S, Chitturi C, Yee J (2019) Vaccination in chronic kidney disease. Adv Chronic Kidney Dis 26:72–78. https://doi.org/10.1053/j.ackd.2018.10.002
doi: 10.1053/j.ackd.2018.10.002
pubmed: 30876620