Venous Thromboembolism in Sickle Cell Disease is Associated with Neutrophilia.
Leukocytosis
neutrophilia
predictors
sickle cell disease
venous thromboembolism (VTE)
Journal
Hemoglobin
ISSN: 1532-432X
Titre abrégé: Hemoglobin
Pays: England
ID NLM: 7705865
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
pubmed:
17
2
2021
medline:
18
12
2021
entrez:
16
2
2021
Statut:
ppublish
Résumé
Venous thromboembolism (VTE) in individuals with sickle cell disease is common and portends a poor prognosis. The role of leukocyte count and its subsets on risk of VTE in sickle cell disease are not known. We conducted a retrospective case-control study and analyzed for leukocyte count at the time of VTE and 3 months prior. Leukocyte and neutrophil counts were elevated at the time of VTE (
Identifiants
pubmed: 33588667
doi: 10.1080/03630269.2020.1869565
pmc: PMC8842825
mid: NIHMS1769242
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
56-59Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL142647
Pays : United States
Organisme : NIDDK NIH HHS
ID : T32 DK060445
Pays : United States
Organisme : NIDDK NIH HHS
ID : T32 DK083266
Pays : United States
Références
Nat Med. 2010 Aug;16(8):887-96
pubmed: 20676107
Blood. 2012 Oct 4;120(14):2879-88
pubmed: 22833547
J Thromb Haemost. 2017 Jul;15(7):1307-1316
pubmed: 28671346
Br J Haematol. 2003 Oct;123(2):359-65
pubmed: 14531921
Am J Med. 2013 May;126(5):443-9
pubmed: 23582935
Br J Haematol. 2012 May;157(3):370-80
pubmed: 22360627
Nat Med. 2017 Mar 7;23(3):279-287
pubmed: 28267716
Blood. 1998 Jun 1;91(11):4216-23
pubmed: 9596669
Immunity. 2019 Jun 18;50(6):1401-1411.e4
pubmed: 31076358
Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15880-5
pubmed: 20798043
Blood. 2012 Jul 19;120(3):636-46
pubmed: 22661702
Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3047-51
pubmed: 11880644
Blood. 2016 Mar 10;127(10):1371-3
pubmed: 26817955
Br J Haematol. 2017 Jul;178(2):319-326
pubmed: 28369826
Blood. 2014 Jun 12;123(24):3818-27
pubmed: 24620350