[Nociception pain and autism].
Nociception, douleur et autisme.
Journal
Medecine sciences : M/S
ISSN: 1958-5381
Titre abrégé: Med Sci (Paris)
Pays: France
ID NLM: 8710980
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
entrez:
16
2
2021
pubmed:
17
2
2021
medline:
27
10
2021
Statut:
ppublish
Résumé
Autistic subjects frequently display sensory anomalies. Those regarding nociception and its potential outcome, pain, are of crucial interest. Indeed, because of numerous comorbidities, autistic subjects are more often exposed to painful situation. Despite being often considered as less sensitive, experimental studies evaluating this point are failing to reach consensus. Using animal model can help reduce variability and bring, regarding autism, an overview of potential alterations of the nociceptive system at the cellular and molecular level. Nociception, douleur et autisme. Les sujets autistes présentent fréquemment des anomalies sensorielles. Celles concernant la nociception ainsi que sa potentielle résultante, la douleur, sont d’un intérêt capital. En effet, du fait de nombreuses comorbidités, les sujets autistes sont plus souvent exposés à des situations douloureuses que la population générale. Alors qu’ils sont souvent considérés comme moins sensibles, les études expérimentales sur ce point sont loin de faire consensus. Utiliser des modèles animaux pourrait permettre de s’affranchir de certaines sources de variabilité et d’apporter, dans le cadre de l’autisme, une vue d’ensemble des altérations potentielles du système nociceptif aux niveaux cellulaire et moléculaire.
Autres résumés
Type: Publisher
(fre)
Nociception, douleur et autisme.
Identifiants
pubmed: 33591257
doi: 10.1051/medsci/2020280
pii: msc200168
doi:
Types de publication
Journal Article
Review
Langues
fre
Sous-ensembles de citation
IM
Pagination
141-151Informations de copyright
© 2021 médecine/sciences – Inserm.
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