Multiple breath washout (MBW) testing using sulfur hexafluoride: reference values and influence of anthropometric parameters.


Journal

Thorax
ISSN: 1468-3296
Titre abrégé: Thorax
Pays: England
ID NLM: 0417353

Informations de publication

Date de publication:
04 2021
Historique:
received: 27 02 2020
revised: 07 01 2021
accepted: 20 01 2021
pubmed: 18 2 2021
medline: 10 7 2021
entrez: 17 2 2021
Statut: ppublish

Résumé

Multiple breath washout (MBW) using sulfur hexafluoride (SF We evaluated cross-sectional data from 100 pulmonary healthy never-smokers and smokers (mean 51 (SD 20), range 20-88 years). Lung clearance index (LCI), acinar (S Age was the only meaningful parameter influencing SF SF NCT04099225.

Sections du résumé

BACKGROUND
Multiple breath washout (MBW) using sulfur hexafluoride (SF
METHODS
We evaluated cross-sectional data from 100 pulmonary healthy never-smokers and smokers (mean 51 (SD 20), range 20-88 years). Lung clearance index (LCI), acinar (S
RESULTS
Age was the only meaningful parameter influencing SF
CONCLUSION
SF
TRIAL REGISTRATION NUMBER
NCT04099225.

Identifiants

pubmed: 33593931
pii: thoraxjnl-2020-214717
doi: 10.1136/thoraxjnl-2020-214717
doi:

Substances chimiques

Sulfur Hexafluoride WS7LR3I1D6

Banques de données

ClinicalTrials.gov
['NCT04099225']

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

380-386

Informations de copyright

© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: The following financial activities outside the submitted work exist: FT received travel support from Actelion, Berlin Chemie, Boehringer Ingelheim, Chiesi, Novartis, Mundipharma and TEVA, as well as speaker or consultation fees from AstraZeneca, Berlin Chemie, Boehringer Ingelheim, Bristol-Myers Squibb, Chiesi, GlaxoSmithKline, Roche, Novartis and Sanofi-Aventis. JoS received travel support and speaker fees from Boehringer Ingelheim, GlaxoSmithKline, Novartis and Roche. MB received speaker or consultation fees from Bayer, Boehringer Ingelheim, Daiichi Sankyo, Impulse Dynamics and Zoll Medical. IA received travel support as well as speaker or consultation fees from Abiomed, Bayer, Boehringer Ingelheim and St Jude Medical.

Auteurs

Frederik Trinkmann (F)

1st Department of Medicine, University Medical Centre Mannheim, Mannheim, Baden-Württemberg, Germany frederik.trinkmann@umm.de.
Department of Pneumology and Critical Care Medicine, Thoraxklinik at University Hospital Heidelberg, Translational Lung Research Centre Heidelberg (TLRC), Member of German Centre for Lung Research (DZL), Heidelberg, Baden-Württemberg, Germany.
Department of Biomedical Informatics, Centre for Preventive Medicine & Digital Health Baden-Württemberg, University Medical Centre Mannheim, Mannheim, Germany.

Máté Maros (M)

Department of Biomedical Informatics, Centre for Preventive Medicine & Digital Health Baden-Württemberg, University Medical Centre Mannheim, Mannheim, Germany.
Department of Neuroradiology, University Medical Centre Mannheim, Mannheim, Germany.

Katharina Roth (K)

1st Department of Medicine, University Medical Centre Mannheim, Mannheim, Baden-Württemberg, Germany.

Arne Hermanns (A)

1st Department of Medicine, University Medical Centre Mannheim, Mannheim, Baden-Württemberg, Germany.

Julia Schäfer (J)

1st Department of Medicine, University Medical Centre Mannheim, Mannheim, Baden-Württemberg, Germany.

Joshua Gawlitza (J)

Institute for Clinical Radiology and Nuclear Medicine, University Medical Centre Mannheim, Mannheim, Germany.

Joachim Saur (J)

1st Department of Medicine, University Medical Centre Mannheim, Mannheim, Baden-Württemberg, Germany.

Ibrahim Akin (I)

1st Department of Medicine, University Medical Centre Mannheim, Mannheim, Baden-Württemberg, Germany.
DZHK (German Centre for Cardiovascular Research), Mannheim, Germany.

Martin Borggrefe (M)

1st Department of Medicine, University Medical Centre Mannheim, Mannheim, Baden-Württemberg, Germany.
DZHK (German Centre for Cardiovascular Research), Mannheim, Germany.

Felix J F Herth (FJF)

Department of Pneumology and Critical Care Medicine, Thoraxklinik at University Hospital Heidelberg, Translational Lung Research Centre Heidelberg (TLRC), Member of German Centre for Lung Research (DZL), Heidelberg, Baden-Württemberg, Germany.

Thomas Ganslandt (T)

Department of Biomedical Informatics, Centre for Preventive Medicine & Digital Health Baden-Württemberg, University Medical Centre Mannheim, Mannheim, Germany.

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Classifications MeSH