Association between lung function of school age children and short-term exposure to air pollution and pollen: the PARIS cohort.
respiratory measurement
Journal
Thorax
ISSN: 1468-3296
Titre abrégé: Thorax
Pays: England
ID NLM: 0417353
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
received:
10
06
2020
revised:
12
01
2021
accepted:
28
01
2021
pubmed:
18
2
2021
medline:
18
9
2021
entrez:
17
2
2021
Statut:
ppublish
Résumé
Daily levels of ambient air pollution and pollen may affect lung function but have rarely been studied together. We investigated short-term exposure to pollen and air pollution in relation to lung function in school-age children from a French population-based birth cohort. This study included 1063 children from the PARIS (Pollution and Asthma Risk: an Infant Study) cohort whose lung function and FeNO measurements were performed at age 8 years old. Exposure data were collected up to 4 days before testing. We estimated daily total pollen concentration, daily allergenic risk indices for nine pollen taxa, as well as daily concentrations of three air pollutants (particulate matter less than 10 µm (PM Four clusters of exposure were identified: no pollen and low air pollution (Cluster 1), grass pollen (Cluster 2), PM Daily ambient chemical and biological air quality could adversely influence lung function in children.
Sections du résumé
BACKGROUND
Daily levels of ambient air pollution and pollen may affect lung function but have rarely been studied together. We investigated short-term exposure to pollen and air pollution in relation to lung function in school-age children from a French population-based birth cohort.
METHODS
This study included 1063 children from the PARIS (Pollution and Asthma Risk: an Infant Study) cohort whose lung function and FeNO measurements were performed at age 8 years old. Exposure data were collected up to 4 days before testing. We estimated daily total pollen concentration, daily allergenic risk indices for nine pollen taxa, as well as daily concentrations of three air pollutants (particulate matter less than 10 µm (PM
RESULTS
Four clusters of exposure were identified: no pollen and low air pollution (Cluster 1), grass pollen (Cluster 2), PM
CONCLUSION
Daily ambient chemical and biological air quality could adversely influence lung function in children.
Identifiants
pubmed: 33593932
pii: thoraxjnl-2020-215515
doi: 10.1136/thoraxjnl-2020-215515
doi:
Substances chimiques
Particulate Matter
0
Ozone
66H7ZZK23N
Nitrogen Dioxide
S7G510RUBH
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
887-894Commentaires et corrections
Type : CommentIn
Informations de copyright
© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: HA, NB, MT, NBe, IM and FR have nothing to disclose. GL reports personal fees from Novartis Pharma, personal fees from AstraZeneca, personal fees from YSSUP research, during the conduct of the study; personal fees from DBV technologies, personal fees from Aimune therapeutics, outside the submitted work. MB-H reports personal fees from Stallergene, personal fees from ALK, outside the submitted work; personal fees and non-financial support from Stallergene, personal fees and non-financial support from ALK, non-financial support from Astra Zeneca, outside the submitted work. JJ reports grants and personal fees from Novartis, grants and personal fees from AstraZeneca, personal fees from ALK, personal fees from Thermofischer, outside the submitted work.