Probiotic
Saccharomyces boulardii supernatant
apoptosis
gastric cancer cells
survivin gene expression
Journal
Food science & nutrition
ISSN: 2048-7177
Titre abrégé: Food Sci Nutr
Pays: United States
ID NLM: 101605473
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
15
08
2020
revised:
12
10
2020
accepted:
10
11
2020
entrez:
18
2
2021
pubmed:
19
2
2021
medline:
19
2
2021
Statut:
epublish
Résumé
Natural anticancer drug and compounds with other great benefits are of interest recently due to lower side effects than chemotherapy for cancer treatment and prevention. Different natural and synthetic drugs have been suggested to be used for treatment of gastric cancers, the second deadly cancer worldwide. The aim of this study was to investigate anticancer activity of SBS including inducing apoptosis and inhibition of survivin gene expression in gastric cancer cells. We evaluated cell viability, inducing apoptosis and change in survivin gene expression of EPG85-257P (EPG) and EPG85-257RDB (resistant to Daunorubicin, RDB) cell lines under exposure of SBS after 24, 48, and 72 hr. We found that SBS decreased cell viability, induced apoptosis, and reduced survivin gene expression in treated EPG and RDB cells (with the significant IC
Identifiants
pubmed: 33598154
doi: 10.1002/fsn3.2032
pii: FSN32032
pmc: PMC7866606
doi:
Types de publication
Journal Article
Langues
eng
Pagination
692-700Informations de copyright
© 2020 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC.
Déclaration de conflit d'intérêts
All authors declare that they have no conflict of interest.
Références
PLoS One. 2016 May 19;11(5):e0155772
pubmed: 27196402
Curr Protoc Immunol. 2016 Feb 02;112:14.38.1-14.38.24
pubmed: 26836509
Anticancer Res. 2019 Jul;39(7):3373-3378
pubmed: 31262858
PLoS One. 2012;7(8):e43483
pubmed: 22916270
J Drug Target. 2017 Jul;25(6):541-553
pubmed: 28277825
J BUON. 2019 Jan-Feb;24(1):221-226
pubmed: 30941973
Cancer Inform. 2019 Apr 19;18:1176935119842576
pubmed: 31037025
Nutr Cancer. 2018 May-Jun;70(4):632-642
pubmed: 29697280
Int J Mol Sci. 2017 Sep 29;18(10):
pubmed: 28961193
Aliment Pharmacol Ther. 2007 Sep 15;26(6):767-78
pubmed: 17767461
Nutr Cancer. 2018 Jan;70(1):83-96
pubmed: 29144773
Gastroenterology. 2009 Sep;137(3):914-23
pubmed: 19482027
J Cell Sci. 2019 Apr 4;132(7):
pubmed: 30948431
Med Res Rev. 2019 May;39(3):887-909
pubmed: 30421440
Food Chem Toxicol. 2012 Sep;50(9):3375-83
pubmed: 22750388
Cancer Med. 2018 Jan;7(1):123-133
pubmed: 29239137
Med Mycol Case Rep. 2017 Jul 25;18:15-17
pubmed: 28794958
J Enzyme Inhib Med Chem. 2014 Apr;29(2):153-61
pubmed: 23368763
Curr Top Med Chem. 2017;17(29):3190-3198
pubmed: 29243581
Cochrane Database Syst Rev. 2017 Aug 29;8:CD004064
pubmed: 28850174
Int J Biol Macromol. 2015 Sep;80:23-8
pubmed: 26092171
Cancer Cell Int. 2016 Jun 23;16:49
pubmed: 27340370
Curr Opin Pharmacol. 2018 Dec;43:87-92
pubmed: 30219638
Trends Cancer. 2017 Dec;3(12):857-870
pubmed: 29198441
Tumour Biol. 2017 Jul;39(7):1010428317714626
pubmed: 28671042
Apoptosis. 2017 Dec;22(12):1487-1509
pubmed: 29067538
Clin Gastroenterol Hepatol. 2020 Mar;18(3):534-542
pubmed: 31362118
Lancet. 2016 Nov 26;388(10060):2654-2664
pubmed: 27156933
Pestic Biochem Physiol. 2017 Jun;139:1-8
pubmed: 28595916