Depression and Viral Suppression Among Adults Living with HIV in Tanzania.
Depression
Gender
Sub-Saharan Africa
Tanzania
Viral suppression
Journal
AIDS and behavior
ISSN: 1573-3254
Titre abrégé: AIDS Behav
Pays: United States
ID NLM: 9712133
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
accepted:
03
02
2021
pubmed:
19
2
2021
medline:
8
9
2021
entrez:
18
2
2021
Statut:
ppublish
Résumé
Limited information is available on the association between depression and viral suppression among people living with HIV (PLH) in sub-Saharan Africa. We conducted a prospective cohort study of 3996 adults initiating antiretroviral therapy (ART) in Dar es Salaam, Tanzania. Log-binomial models were used to assess the association between depression and the risk of an unsuppressed viral load (> 400 copies/mL) after 6 months of ART. Women who had depression at both initiation and after 6 months of treatment had 1.94 times (95% CI 1.22, 3.09; z = 2.78, p < 0.01) the risk of an unsuppressed viral load after 6 months of treatment as compared to women who did not have depression at either time point. Men with the top tertile of depressive symptoms after 6 months of treatment had 1.58 times the risk of an unsuppressed viral load (95% CI 1.04, 2.38; z = 2.15, p = 0.03) as compared to the lowest tertile. Research should be pursued on interventions to prevent and address depression among adults initiating ART to potentially support achievement of viral suppression.
Identifiants
pubmed: 33598866
doi: 10.1007/s10461-021-03187-y
pii: 10.1007/s10461-021-03187-y
pmc: PMC8368084
mid: NIHMS1703368
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3097-3105Subventions
Organisme : NIDDK NIH HHS
ID : R01 DK098075
Pays : United States
Organisme : NIAID NIH HHS
ID : T32 AI007358
Pays : United States
Organisme : NIH HHS
ID : 5T32AI007358 - 32
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01DK098075
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01DK098075
Pays : United States
Organisme : NIH HHS
ID : 5T32AI007358 - 32
Pays : United States
Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature.
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