Simultaneous double laryngeal tumours: a diagnostic and therapeutic challenge.

ear, nose and throat/otolaryngology head and neck cancer head and neck surgery pathology surgical oncology

Journal

BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291

Informations de publication

Date de publication:
18 Feb 2021
Historique:
entrez: 19 2 2021
pubmed: 20 2 2021
medline: 15 5 2021
Statut: epublish

Résumé

Leiomyosarcomas are soft tissue tumours that rarely occur in the larynx. This case report describes the presentation and management of a 77-year-old man referred to the otolaryngology clinic with hoarseness who was found to have a large supraglottic leiomyosarcoma after panendoscopy and biopsies. He subsequently underwent laryngectomy for treatment of this tumour but, unexpectedly, the histological analysis of the laryngectomy specimen revealed a second primary tumour in the larynx-a squamous cell carcinoma (SCC). The patient had further treatment with neck radiotherapy. Three years after treatment, there are no signs of recurrence of either tumour. This case report discusses the very few similar cases of leiomyosarcoma coexisting with SCC in the larynx, collating the evidence surrounding the treatment of this rare presentation.

Identifiants

pubmed: 33602770
pii: 14/2/e239797
doi: 10.1136/bcr-2020-239797
pmc: PMC7896599
pii:
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

J Laryngol Otol. 1986 Aug;100(8):915-8
pubmed: 3746107
Auris Nasus Larynx. 2009 Apr;36(2):239-43
pubmed: 18617340
Ann Otol Rhinol Laryngol. 1999 Jul;108(7 Pt 1):677-82
pubmed: 10435928
Mol Med Rep. 2012 Apr;5(4):971-3
pubmed: 22307748
Ann Otol Rhinol Laryngol. 1999 Aug;108(8):794-6
pubmed: 10453789
Ecancermedicalscience. 2016 Apr 25;10:636
pubmed: 27170836
J Laryngol Otol. 2008 Jan;122(1):93-6
pubmed: 17359556
J Laryngol Otol. 1983 Jul;97(7):619-21
pubmed: 6875363
Head Neck. 1994 Sep-Oct;16(5):453-6
pubmed: 7960744
Acta Otorhinolaryngol Ital. 1994 Mar-Apr;14(2):157-65
pubmed: 7976325
B-ENT. 2005;1(3):145-9
pubmed: 16255499
AJR Am J Roentgenol. 2008 Sep;191(3 Suppl):S18-21
pubmed: 18716068
J Coll Physicians Surg Pak. 2020 Aug;30(8):871-873
pubmed: 32893803
AJNR Am J Neuroradiol. 1996 Jun-Jul;17(6):1112-4
pubmed: 8791924
Arch Otolaryngol. 1981 Mar;107(3):135-7
pubmed: 7469898
Eur Arch Otorhinolaryngol. 1997;254(9-10):466-9
pubmed: 9438120
J Laryngol Otol. 2013 Aug;127(8):828-31
pubmed: 23919956
BMJ Case Rep. 2020 Nov 30;13(11):
pubmed: 33257390
Arch Otolaryngol. 1973 May;97(5):420-2
pubmed: 4703540

Auteurs

Fergus Cooper (F)

Otolaryngology, Aberdeen Royal Infirmary, Aberdeen, UK fergus.cooper2@nhs.scot.

Rafael Moleron (R)

Oncology, Aberdeen Royal Infirmary, Aberdeen, UK.

Andrea Chapman (A)

Pathology, Aberdeen Royal Infirmary, Aberdeen, UK.

Muhammad Shakeel (M)

Otolaryngology, Aberdeen Royal Infirmary, Aberdeen, UK.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH