The dural sinus hub: more than just a brain drain.


Journal

Cell
ISSN: 1097-4172
Titre abrégé: Cell
Pays: United States
ID NLM: 0413066

Informations de publication

Date de publication:
18 02 2021
Historique:
entrez: 19 2 2021
pubmed: 20 2 2021
medline: 19 8 2021
Statut: ppublish

Résumé

Recent findings of an active neuroimmune exchange at brain border regions have challenged the concept of the immune-privileged central nervous system. The study by Rustenhoven et al. in this issue of Cell shows that dural sinuses serve as a conduit for brain-derived antigens to interact with the immune system, allowing in situ immune surveillance.

Identifiants

pubmed: 33606985
pii: S0092-8674(21)00083-0
doi: 10.1016/j.cell.2021.01.040
pii:
doi:

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

858-860

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Sarah Mundt (S)

Institute of Experimental Immunology, University of Zurich, 8057 Zurich, Switzerland.

Annika Keller (A)

Department of Neurosurgery, Clinical Neuroscience Center, University Hospital Zurich, University of Zurich, 8952 Schlieren, Switzerland.

Melanie Greter (M)

Institute of Experimental Immunology, University of Zurich, 8057 Zurich, Switzerland. Electronic address: greter@immunology.uzh.ch.

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Classifications MeSH