COVID-19-from mucosal immunology to IBD patients.
Journal
Mucosal immunology
ISSN: 1935-3456
Titre abrégé: Mucosal Immunol
Pays: United States
ID NLM: 101299742
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
received:
04
10
2020
accepted:
05
01
2021
revised:
11
12
2020
pubmed:
21
2
2021
medline:
11
5
2021
entrez:
20
2
2021
Statut:
ppublish
Résumé
Viral infections with SARS-CoV-2 can cause a multi-facetted disease, which is not only characterized by pneumonia and overwhelming systemic inflammatory immune responses, but which can also directly affect the digestive system and infect intestinal epithelial cells. Here, we review the current understanding of intestinal tropism of SARS-CoV-2 infection, its impact on mucosal function and immunology and summarize the effect of immune-suppression in patients with inflammatory bowel disease (IBD) on disease outcome of COVID-19 and discuss IBD-relevant implications for the clinical management of SARS-CoV-2 infected individuals.
Identifiants
pubmed: 33608656
doi: 10.1038/s41385-021-00384-9
pii: S1933-0219(22)00158-1
pmc: PMC7893623
doi:
Substances chimiques
Biomarkers
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
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