Muscle-invasive Bladder Cancer in the Elderly Patient With a Focus on Hypofractionated Radiotherapy.
Elderly
hypofractionated radiotherapy
muscle-invasive bladder cancer
palliative radiotherapy
Journal
Clinical oncology (Royal College of Radiologists (Great Britain))
ISSN: 1433-2981
Titre abrégé: Clin Oncol (R Coll Radiol)
Pays: England
ID NLM: 9002902
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
received:
06
01
2021
revised:
25
01
2021
accepted:
03
02
2021
pubmed:
23
2
2021
medline:
26
11
2021
entrez:
22
2
2021
Statut:
ppublish
Résumé
Muscle-invasive bladder cancer is most frequently diagnosed in older patients and the presence of multimorbidity and frailty is common. This means that many patients are unsuitable for definitive treatment with radical cystectomy/(chemo)radiotherapy and are at risk of poor survival outcomes and considerable disease-related morbidity. Screening tools for functional status may be useful to determine the most appropriate treatment for an older person and to identify patients most likely to benefit from comprehensive geriatric assessment and its targeted prehabilitation interventions. For patients unsuitable for definitive treatment, ultrahypofractionated radiotherapy schedules may provide good local control with acceptable toxicity. Short fractionated palliative radiotherapy schedules can provide effective symptom control for patients unsuitable for longer courses of treatment.
Identifiants
pubmed: 33612421
pii: S0936-6555(21)00045-5
doi: 10.1016/j.clon.2021.02.002
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
369-375Informations de copyright
Copyright © 2021 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.