Routine Measurement of Thyroid Stimulating Hormone in Patients Presenting With Third-Degree Atrioventricular Block: Do We Really Need It?

atrioventricular block complete heart block permanent pacemakers thyroid stimulating hormone tsh

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
14 Jan 2021
Historique:
entrez: 22 2 2021
pubmed: 23 2 2021
medline: 23 2 2021
Statut: epublish

Résumé

Background Hypothyroidism can be a cause of sinus bradycardia. However, thyroid laboratory evaluation is often performed routinely in patients with complete heart block (CHB) though there is little data to support this practice. This study aimed to assess the frequency of thyroid dysfunction in patients presenting with CHB without clinical features of hypothyroidism. Methodology All patients referred for permanent pacemaker implantation for CHB were included in this cross-sectional study. Patients with known thyroid disorder or clinical features of thyroid disorder were excluded. Demographic, electrocardiography (EKG), and routine thyroid stimulating hormone (TSH) screening results were recorded. Results A total of 102 patients with complete atrioventricular (AV) block were enrolled in the study of which 50.0% (51) were male. The mean age was 61.09 ± 11.74. Co-morbidities included diabetes mellitus 44.1% (45), smoking 36.3% (37), and hypertension 55.9% (57). Mean EKG atrial rate was 82.97 ± 31.31 mmHg with a mean ventricular escape rate of 36.17 ± 5.93. Permanent pacemakers were implanted in all of the patients. Only one patient had an abnormal TSH. Conclusions We found a very low prevalence of thyroid dysfunction among patients without clinical features of thyroid dysfunction presenting with third-degree AV block. This calls for cautious prescription of thyroid testing in clinically euthyroid patients.

Identifiants

pubmed: 33614317
doi: 10.7759/cureus.12712
pmc: PMC7883583
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e12712

Informations de copyright

Copyright © 2021, Faisal et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

Prog Cardiovasc Dis. 1964 Mar;6:409-44
pubmed: 14153648
Circ Arrhythm Electrophysiol. 2018 Jul;11(7):e006273
pubmed: 29954742
Eur Heart J. 2013 Jan;34(2):138-46
pubmed: 22947613
JAMA. 2009 Jun 24;301(24):2571-7
pubmed: 19549974
Nouv Presse Med. 1975 Jun 21;4(25):1859-62
pubmed: 1153322
Chest. 1973 Apr;63(4):582-5
pubmed: 4695358
J Am Coll Cardiol. 1986 Jan;7(1):180-4
pubmed: 3941210
Circulation. 1965 Jun;31:888-98
pubmed: 14297523
Endocrinol Metab (Seoul). 2014 Mar;29(1):20-9
pubmed: 24741450
Eur Heart J. 2005 Nov;26(21):2300-6
pubmed: 16214833
Pacing Clin Electrophysiol. 2006 Jan;29(1):106-8
pubmed: 16441726
Neth Heart J. 2008 Feb;16(2):57-9
pubmed: 18335023
Prog Cardiovasc Dis. 1964 Jan;6:317-26
pubmed: 14105712
Br Med J. 1963 Nov 9;2(5366):1149-53
pubmed: 14060910
J Am Coll Cardiol. 2019 Aug 20;74(7):932-987
pubmed: 30412710
JAMA Netw Open. 2019 May 3;2(5):e194176
pubmed: 31125096
J Cardiol. 2012 Oct;60(4):327-32
pubmed: 22738687

Auteurs

Muhammad Faisal (M)

Electrophysiology, National Institute of Cardiovascular Diseases, Karachi, PAK.

Zubair Mumtaz (Z)

Electrophysiology, National Institute of Cardiovascular Diseases, Karachi, PAK.

Abdul Mueed (A)

Electrophysiology, National Institute of Cardiovascular Diseases, Karachi, PAK.

Sajid Ali (S)

Electrophysiology, National Institute of Cardiovascular Diseases, Karachi, PAK.

Haseeb H Raza (HH)

Electrophysiology, National Institute of Cardiovascular Diseases, Karachi, PAK.

Samra Khan (S)

Medicine, Liaquat National Hospital, Karachi, PAK.

Sayeda Salma (S)

Cardiology, National Institute of Cardiovascular Diseases, Karachi, PAK.

Mustajab Mujtaba (M)

Cardiology, National Institute of Cardiovascular Diseases, Karachi, PAK.

Musa Karim (M)

Research, National Institute of Cardiovascular Diseases, Karachi, PAK.

Faisal Qadir (F)

Electrophysiology, National Institute of Cardiovascular Diseases, Karachi, PAK.

Classifications MeSH