Cellular Diversity and Regeneration in Taste Buds.
ATP
LGR5
SOX2
Sonic Hedgehog
Taste Receptors
WNT
adult stem cells
neurotransmitter
Journal
Current opinion in physiology
ISSN: 2468-8673
Titre abrégé: Curr Opin Physiol
Pays: England
ID NLM: 101715200
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
entrez:
22
2
2021
pubmed:
23
2
2021
medline:
23
2
2021
Statut:
ppublish
Résumé
Taste buds are the sensory end organs for gustation, mediating sensations of salty, sour, bitter, sweet and umami as well as other possible modalities, e.g. fat and kokumi. Understanding of the structure and function of these sensory organs has increased greatly in the last decades with advances in ultrastructural methods, molecular genetics, and in vitro models. This review will focus on the cellular constituents of taste buds, and molecular regulation of taste bud cell renewal and differentiation.
Identifiants
pubmed: 33615087
doi: 10.1016/j.cophys.2021.01.003
pmc: PMC7888981
mid: NIHMS1662315
doi:
Types de publication
Journal Article
Langues
eng
Pagination
146-153Subventions
Organisme : NCI NIH HHS
ID : R21 CA236480
Pays : United States
Organisme : NIDCD NIH HHS
ID : R01 DC018489
Pays : United States
Organisme : NIDCD NIH HHS
ID : R01 DC014728
Pays : United States
Organisme : NIDCD NIH HHS
ID : R01 DC012383
Pays : United States
Organisme : NIDCD NIH HHS
ID : R01 DC017679
Pays : United States
Déclaration de conflit d'intérêts
COI Statement The authors (LB and TF) declare no conflicts of interest.
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